Kitayama S, Morita K, Dohi T, Tsujimoto A (1986b) Potassium ion is indispensable to the catecholamine releasing response of dog adrenals to γ-aminobutyric acid. Naunyn-Schmiedeberg's Arch Pharmacol 332:66–69Kitayama S, Morita K, Dohi T, Tsujimoto A (1986a) Potassium ion is indispensable ...
25. Covington AK, Robinson RA (1975) References standards for the electrometric determination, with ion-selective electrodes, of potassium and calcium in blood serum. Anal Chim Acta 78:219–223. https://doi.org/10.1016/...
PD-L2 expression is detectable in a large variety of human cancers, being most prominent in triple-negative breast cancer, and head and neck squamous cell carcinomas7,12. There is limited understanding about the biological role of PD-L2 for immune evasion in cancers, although ectopic expression ...
6c), or in the presence of a dominant-negative mutation L265P8 (Fig. 6c), indicating that the NAADP-evoked inward Na+ currents were mostly originated from the plasma membrane-targeted TPC2PM channels. Consistent with Lsm12 as the NAADP receptor, the NAADP-induced TPC currents in TPC2-...
Apoptosis is a special form of cell death that if non-functional may lead to diseases such as cancer. A reduction of the intracellular potassium ion (K+) c... B Andersson - Medicinsk biovetenskap 被引量: 0发表: 2007年 Acquisition of cisplatin-resistance in malignant mesothelioma cells abrogat...
Using a forward genetic screen to identify mutant T. gondii parasites resistant monensin, Garrison and Arrizabalaga found that the disruption of a mitochondrial DNA repair enzyme (TgMSH-1) contributed to parasite resistance to both monensin and the potassium ionophore salinomycin (Garrison and ...
The microsomal pellet was resuspended in resuspension buffer I (0.33 M Sucrose, 3 mM KCl, 0.1 mM EDTA, 2 mM DTT, 1 mM PMSF, and 5 mM Potassium-phosphate, pH 7.5). The suspension was mixed with two-phase buffer (0.33 M Sucrose, 6.2% (w/w) Dextran T-500, 6.2% (w/w) PEG3350,...
The gradual shift of inactivation curve towards negative potentials would make the holding potential progressively inactivate the channel, resulting in apparent loss of activity of the channels. Our results thus provide a biophysical explanation for rundown of A-type current. Synapse 48:57-65, 2003....
mCh-Atg8a-marked autophagic vesicles in these cells are not enlarged relative to those in the surrounding GFP-negative control cells. N=7. In a and e, nuclei are labelled in blue with DAPI; scale bars, 10 μm. (f) High-magnification confocal images of mCh-Atg8a-positive vesicles in...
It was shown that potassium channels regulate membrane potential, ion homeostasis, and electric signaling52,53. Furthermore, the presence and also activity of ion pumps/ channels has correlation with the cancer development via its proliferation, differentiation, apoptosis, and migration54. In cBioportal...