Two-pore-domain (K(2P)) potassium channels mediate background potassium currents, stabilizing resting membrane potential and expediting action potential repolarization. In the heart, K(2P)3.1 (TASK-1) channels are implicated in the cardiac plateau current, I ( KP ). Class III antiarrhythmic drugs...
). DE analysis revealed no significant differences between DMSO (vehicle) and potassium simplex optimized medium (KSOM) (control) embryos, so we performed all subsequent analyses against the DMSO group. Embryos grown with LY2955303 displayed a transcriptional program that differed from controls (...
Zinc (Zn) is an essential trace element in living organisms and plays a vital role in the regulation of both microbial virulence and host immune responses. A growing number of studies have shown that zinc deficiency or the internal Zn concentration does not meet the needs of animals and microb...
Here, we show that mouseZftais expressed in embryonic immature ependymal (pre-E1) cells, possibly under the control of ciliary transcription factors (TFs).Zftatm1knock-in mice are apparently normal in their development and fertilisation. Our study suggests a molecular mechanism by which ZFTA-RELA...
The small conductance calcium-activated potassium channel 3 (SK3) is a molecular target for Edelfosine to reduce the invasive potential of urothelial carcinoma cells. Tumour Biol. 2016;37: 6275-83.
ABA responsive element binding fa... XS Huang,LXJ Chen - 《Bmc Plant Biology》 被引量: 282发表: 2010年 Cloning and molecular characterization of a mitogen-activated protein kinase gene from Poncirus trifoliata whose ectopic expression confers dehydration/dro... The mitogen-activated protein kinase ...
[1]. In general, environmental signals, such as low temperatures and short-day control endodormancy induction and maintenance [2]. The effective accumulation of low temperature and several chemicals, such as hydrogen cyanamide (HC), mineral oil, potassium nitrate, gibberellin (GA) and 5-...
Innate immune responses are evolutionarily conserved processes that provide crucial protection against invading organisms. Gene activation by potent NF-κB transcription factors is essential both in mammals and Drosophila during infection and stress chal
while the interaction between each two nodes was represented by a gray line connecting them. The node was colored with blue, yellow, orange, or purple if the corresponding element possessed the highest expression or abundance before incubation, on the third, seventh, or twenty-eighth day after ...
These 61 serpentine adaptation candidates were significantly enriched (p < 0.05) for categories related, for example, to regulation of ion transmembrane transport, and specifically, voltage-gated calcium and potassium channel activity (Supplementary Data 7). Candidates included the NRT2.1 and NRT2.2...