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Hippocampal volume also had a strong negative correlation with the posterior lateral ventricle volume and strong positive correlation with the thickness of CA1 (Fig. 2k,l). Taken together, these data illustrate that removal of neuronal APOE4 protects against tau-mediated neurodegeneration and mitigates...
Inhibition of AMPK is tightly associated with metabolic perturbations upon over nutrition, yet the molecular mechanisms underlying are not clear. Here, we demonstrate the serine/threonine-protein phosphatase 6 regulatory subunit 3, SAPS3, is a negative r
A strong base always forms a weak conjugate acid. A weak acid always forms a strong conjugate base. A weak base always forms a strong conjugate acid. In the case of H3PO4, it forms H2PO4- (dihydrogen phosphate anion) as its conjugate base after removing an acidic proton. ...
Under a Creative Commons license open accessHighlights Abstract The yft1 tomato mutant has a yellow-fruited phenotype controlled by a recessive gene of YFT1 allele, which has been shown by map-based cloning to be a homolog of ETHYLENE INSENSITIVE 2 (EIN2). Genetic lesion of YFT1 allele in...
GC skew diagram for the Helicosporidium plastid genome. The sum of [G-C]/[G+C] calculated in 37 base, non-overlapping adjacent windows is shown superimposed on a linearized scale map of the genome, starting between the LSU and rpoC2 genes. The global minimum of this plot corresponds to...
IFB-2 is an essential component of the apical intestinal IF network, and loss of IFB-2 results in a complete absence of the endotube.19,20 Therefore, the strong reduction in apical BBLN-1 likely reflects the loss of all IFs from the apical domain. We also examined BBLN-1 in the ...
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