“The consequences are huge,” says biophysicistHolger Dauat the Free University of Berlin in Germany, a co-author on one of the new studies, because it “led to the oxygen-rich atmosphere we have today on Earth.” Oxygen is highly reactive and provides lots of energy to organism...
However, the role of reactive oxygen species (ROS) in biologic systems is entirely dependent on context: location, neighbors, and timing (2). ROS are oxygen ions [singlet oxygen, superoxide (O2·Ϫ)] or oxygen-containing radicals [hydroxyl, OH·Ϫ]. ROS and their reaction products [e....
aROS( reactive oxygen species) are continuously formed via environmental influence and aerobic metabolism. In healthy subject, there is a tightly controlled balance between the generation of ROS and the capacity of the antioxidant protective system, whereas, excessive ROS play an important role in agin...
susceptible to the damaging effects of reactive oxygen species (ROS), which have been implicated in causing DNA deletions22,23,24. In two separate assays we detected slightly higher ROS levels in healthy old and LOAD cells when compared to young controls, which were significant in the old, but...
Rogers H (2012) Is there an important role for reactive oxygen species and redox regulation during floral senescence? Plant Cell Environ 35:217-233Rogers JH (2012) Is there an important role for reactive oxygen species and redox regulation during floral senescence? Plant Cell Environ 35(2):217...
showed that neutralizing diabetes-associated elevation of reactive oxygen species (ROS) in rat diabetic GK islets by antioxidants counteracts the upregulation of the major metabolic transcription factor HIF1α and its downstream target genes including LDHA. Consequently, lactate production decreased, ...
Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species Diabetes, 55 (5) (2006), pp. 1289-1299 CrossrefView in ScopusGoogle Scholar [14] A. Moraru, J. Wiederstein, D. Pfaff, T. Fleming, A.K. Miller, P. Nawroth, et al...
Lifestyle Changes to Help Reactive Hypoglycemia Most people don’t need medical treatment to manage reactive hypoglycemia. Instead, there are changes you can make at home. Often changing your diet can help your symptoms. Here are some things you can try: ...
Hydrogen peroxide or other reactive oxygen species could cause dilation in hypoxia; however, treating the isolated vessels with the peroxide scavenger TEMPOL did not affect hypoxia-induced dilation for any genotype (Fig. 7h), thus excluding hydrogen peroxide as the vasodilatory signal in this context...
The persistence of respiratory function under Cys limitation potentiates the iron-mediated generation of membrane phospholipid alkoxyl (PLO•) and peroxy (PLOO•) radicals that mediate ferroptosis; GSH glutathione, ROS reactive oxygen species. Data represent mean values ± s.d. For (b–g) ...