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Closo-dodecaborate dianion is athree-dimensional aromatic inorganic molecule, which can be easily halogenated forming astable halogen-boron bond. Derivativ... V Tolmachev,A Bruskin,I Sivaev,... - 《Radiochimica Acta》 被引量: 63发表: 2002年 [N(CH3)4]4H12Ge9O26.14H2O The title compound,...
O-GlcNAcylation and phosphorylation engage in well-documented signaling crosstalk, sometimes competing for identical or nearby residues on the same substrates33,61,62,63,64,65. None of the NF-L O-GlcNAc sites we identified is a validated phosphosite, but NF-L is known to be phosphorylated at ...
3). This assay is based on the fact that the disruption of the glycosyl-enzyme intermediate is the rate-limiting step for rBxTW1-E495A using pNPX as donor14. An acceptor able to speed up this disruption regenerates the ability of the enzyme to catalyze the cleavage of a new molecule ...
The rate constant was found to be independent of temperature with a value of k1=(4 ± 1)× 10–12 cm3 molecule–1 s–1. The likely mechanism for the reaction is discussed. The atmospheric implications of reaction (1) are investigated using a range of models and several case studies are...
Can sucrose cleavage enzymes serve as markers for sink strength and is sucrose a signal molecule during plant sink development? `Department of Biochemistry and h4olecdar Biology%zsrirute of Tree Root Bioiogy, Southern Research Sration, USDA-Forest Service The Univeky of Georgia, Ath... CC Blac...
verified that a novel small-molecule tyrosine kinase inhibitor (TKI), apatinib, could safely act as an antitumour rule in DTC by altering biological behaviour through the PI3K/Akt/mTOR signaling pathway. More importantly, the autophagy effects induced by apatinib could also provide a potential ...
The functional integrity of the FGF2 molecule was assayed by two functional assays, a DF proliferation assay and by measuring the ESM-1 secretion30. When placed at 37 °C for 24 h, soluble FGF2 lost its activity as detected by reduced proliferation and ESM-1 secretion (Fig. 3A). When ...
(Ionized calcium-binding adaptor molecule 1) IBA1+ microglia, without affecting the pSMAD3 immunostaining in IBA1− cells (bottom rows of Fig.1B–Eand quantification in F, G). This specific loss of TGF-β1 signaling (pSMAD3) in microglia from MG-Tgfb1iKO mice confirms that microglia ...