(OAS) hypothesis, whereby older children have B-cell memory due to prior exposure to seasonal coronaviruses, especially in SARS-CoV-2 spike S2 domain as observed in older children, adults, and elderly20,21,22,23. Recently, we observed anti-S2 cross-reactivity in naive older children but ...
International human rights bodies are already facing increasing political pressure, which may lead them to adopt more restrictive positions in refugee and migrant cases. This political pressure may come from countries or political forces that want international human rights bodies to take a more restrict...
For you readers in Illinois, if it seems like there have been a lot of tornadoes in 2023 so far, you are correct. Illinois is the state with the most recorded tornadoes for the year so far, with 97 confirmed tornadoes across the state, USA Today is reporting, up from the 54 tornadoes...
This limits the number of samples that can be sequenced on a weekly basis, increasing the risk of missing emerging variants of potential concern. In addition to its applications for WGS, NGS has also been used for mass-scale SARS-CoV-2 testing, such as in the SwabSeq method20; however, ...
In recent decades, the differential mortality gap associated with schizophrenia has been increasing. It is sobering to reflect on this paradox of schizophrenia treatment. As we become better at detecting and treating the core symptoms of schizophrenia, patients have worsening SMRs. Given the potential...
Intense efforts have been devoted to describe the biochemical pathway of plant sulphur (S) assimilation from sulphate. However, essential information on metabolic regulation of S assimilation is still lacking, such as possible interactions between S assi
The OpenAPI Specification (OAS) establishes an interface for describing an API in a way that allows any developer or application to discover it and fully understand its parameters and capabilities. This information includes available endpoints, allowed operations on each endpoint, operation parameters, ...
All these genes were significantly upregulated in children at baseline (Figure 1C-D). Following SARS-CoV-2 infection, IFITM1, IFIT2, and OAS1 were significantly higher, IFTIM3, IFIT1, ISG20 had an increasing trend, while IFI6 had lower expression in children compared to adults (Figure 5...
As lineages carrying beneficial mutations arise in the population, they accumulate detrimental mutations which prevent them from being effectively selected. This increasing mutational load slows the rate of evolution, an effect known as “Muller’s Ratchet”. Competition between adaptive lineages, or “...
Wt cells treated with rosup (a potent ROS increasing agent) were used as the control. Data were from three independent experiments and presented as average ± SD. T-tests were performed to calculate the p-values, and asterisks indicate statistically significant difference (∗p < 0.05, ∗...