The cannabinergic system is implicated in the mechanisms of action of certain psychotropic drugs including the upregulation of brain NGF levels. This provides a better understanding of the pathophysiological mechanisms underlying neuropsychiatric disorders, leading to novel drug design....
many other Psychotropic agents with dopamine blocking as a mechanism Drugs with anticholinergic effects (sometimes given for dizziness) Tricyclic antidepressants (e.g., amitriptyline, nortriptyline) Transderm Scop Meclizine Miscellaneous drugs amiodarone -- multiple mechanisms including vestibular, neuropathy...
Concomitant use of Marplan and other psychotropic agents is generally not recommended because of possible potentiating effects. This is especially true in patients who may subject themselves to an overdosage of drugs. If combination therapy is needed, careful consideration should be given to the pharm...
Psychotropic drugs, including many antidepressants, are usually lipophilic and are extensively metabolized in the liver through phase I oxidative reactions followed by phase II glucuronide conjugation. Most pharmacokinetic interactions with psychotropic drugs occur at the metabolic level and primarily involve t...
4. Telomeres and Psychotropic Medications 4.1. Lithium and Telomeres Robust preclinical and clinical evidence suggests that lithium may exert a counteractive effect on telomere shortening. Using a preclinical model of telomere dysfunction, Wei and coworkers [71] showed that a six-week lithium treatment...