many other Psychotropic agents with dopamine blocking as a mechanism Drugs with anticholinergic effects (sometimes given for dizziness) Tricyclic antidepressants (e.g., amitriptyline, nortriptyline) Transderm Scop Meclizine Miscellaneous drugs amiodarone -- multiple mechanisms including vestibular, neuropathy...
E-10-hydroxynortriptyline, a metabolite of nortriptyline with half the norepinephrine re-uptake blocking potency of the parent drug, but only 5% of its anticholinergic effect, was as effective as cocaine in demonstrating ocular sympathetic paresis. In five rabbits with unilateral superior cervical ...
Tricyclic antidepressantsare an older class of antidepressants that, while effective for some people, carry a large side effect profile including heart arrhythmias and anticholinergic side effects like dry mouth, sedation, and constipation: Amitriptyline (Amitrip, Elevil, Endep, Levate, Amitril, Enovi...
In the study conducted by Berkenet al., low to moderate doses of the TCAs amitriptyline (150 mg per day), nortriptyline (50 mg per day) and imipramine (80 mg per day) were associated with a mean weight gain of 1.3–2.9 lbs per month, and the trend of weight gain remained li...
Tricyclic antidepressants are an older class of antidepressants that, while effective for some people, carry a large side effect profile including heart arrhythmias and anticholinergic side effects like dry mouth, sedation, and constipation: Amitriptyline (Amitrip, Elevil, Endep, Levate, Amitril, En...
11. Pfandl B, M^rike K, Winne D, et al. Stereoselective inhibition of nortriptyline hydroxylation in man by quinidine.Xenobiotica.1992;22:721-730. 12. Lin JH, Lu AY. Inhibition and induction of cytochrome P450 and the clinical implications.Clin Pharmacokinet.1998;35:361-390. ...
a) Desipramine b) Clomipramine c) Doxepin d) Nortriptyline e) Amitriptyline f) Imipramine g) all of the above Which of the following is NOT a group of drugs used as an antiemetic or antivertigo treatment? a. Antidopaminergic b. Anticho...
Serotonin syndrome remains a clinical diagnosis; thus, there are no diagnostic tests. Other diagnoses in the differential include NMS, malignant hyperthermia, and anticholinergic delirium (TABLE 4). NMS is an idiosyncratic response to neuroleptics resulting in lead-pipe rigidity and hyperpyrexia. NMS...
2008,in248nursinghomeresidentswithdementia.Their meanageoftheparticipantswas82years. TheinvestigatorsextractedtheuseanddoseofSSRIsandotherdrugsknowntoincrease theriskoffalls,includingantipsychotics,anxiolytics,hypnotics,sedatives,antidiabetic drugs,beta-blockereyedrops,cardiovasculardrugs,analgesics,anticholinergics, ...