Re: Is NaCl a base? « Reply #3 on: October 17, 2007, 09:53:55 AM » Cl- can act as a very weak base and accept proton:Cl- + H+ = HClNa+ can act as a weak acid:Na+ + H2O = NaOH + H+and while it is still very weak, it is at least 1000 times stronger acid th...
A weak intermolecular salt bridge is additionally formed between the pY359 phosphate group and K297 of the symmetry related molecule. The electrostatic surface potential surrounding pY359 in HIPK3 is shown in Supplementary Fig. 2b, c. Fig. 3: Coordination of the phosphorylated tyrosine and the ...
The selective genetic removal of APOE4 from neurons led to a significant reduction in tau pathology, gliosis, neurodegeneration, neuronal hyperexcitability and myelin deficits. Single-nucleus RNA-sequencing revealed that the removal of neuronal APOE4 greatly diminished neurodegenerative disease-associated ...
Innate immune responses are evolutionarily conserved processes that provide crucial protection against invading organisms. Gene activation by potent NF-κB transcription factors is essential both in mammals and Drosophila during infection and stress chal
EGFPN1-AIRE-transfected GC1 cells (test) as well as empty-vector-transfected GC1 cells (control) were lysed in RIPA buffer (150 mm NaCl, 1.0% octyl phenoxy polyethoxy ethanol (IGEPAL), 0.5% sodium deoxycholate, 0.1% SDS, and 50 mm Tris, pH 8.0) containing protease inhibitor mixture (...
Why a compromised IF network leads to cytoplasmic invaginations is not clear. One explanation is that pressure from the lumen physically forces invaginations through weak spots in the IF network. However, ifb-2 mutants that lack an apical IF network entirely have a largely normal intestinal morpho...
This explanation is encouraged by our Western blot analysis where breast carcinoma extracts with high PAI-1 protein levels showed weak SERBP1 protein expression by trend and vice versa breast carcinoma extracts with low PAI-1 protein levels showed abundant SERBP1 protein expression. However, this ...
(in four grades: 1, negative; 2, weak; 3, moderate; 4, intense) which results in a value between 0 and 400. Cores with scores 0 (0), 1 to 200 (1), 201 to 300 (2) and 301 to 400 (3) were referred to as negative, low, intermediate, or high protein expression, respectively...
A similar idea was presented in 2003 by Rajagopal and Simon [9] for the ABC transporter multidrug resistance protein 1 (MRP1; ABCC1). It was long known that lysosomes can act as mediators of drug resistance by passive drug sequestration of hydrophobic weak base chemotherapeutics such as ...
A strong base is the one that gives away the hydroxyl ion readily while the weak base loses the ion slowly. But, Ammonia does not behave as either acid or base according to the Bronsted-Lowry theory. As ammonia does not have extra hydroxyl ion to donate, it cannot be classified as a ...