Myeloma is a condition in which the plasma cells in bone marrow become cancerous. The symptoms of myeloma are...
Multiple myeloma, another type of cancer that comes from white blood cells Lead poisoning Rheumatoid arthritis How Is the Red Blood Cell Count Test Done? A blood sample is required for this test. A health care professional uses a needle to draw blood from a vein in your hand or arm. How ...
Genetics plays a role in cancers that seem to “run in families.” Even when cancer is found in multiple members of a family, it does not mean that cancer is being passed from one person to another like a contagious illness. Instead, it may have to do with genes that are passed down ...
In deciding on the optimal source (bone marrow vs peripheral blood) for early and actionable testing, one must consider that a high sensitivity method may detect chimerism kinetics in the BM that are not necessarily indicative of relapse or graft failure. Also, it has been proposed that the hi...
Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-x L/Bcl-2 in Mcl-1-expressing myeloma cells. Blood 2011; 118: 1329–1339. Article CAS Google Scholar Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG . Differential targeting of prosurvival Bcl-2 ...
Leukemia www.nature.com/leu ARTICLE OPEN MULTIPLE MYELOMA, GAMMOPATHIES Efficacy and safety of isatuximab plus bortezomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma ineligible/with no immediate intent for autologous stem cell transplantation Enrique M. Ocio 1 ✉...
CM Linardic,JZ Gong,PM Rosoff - 《Pediatric Blood & Cancer》 被引量: 5发表: 2002年 Decision Analysis of Transplantation for Patients with Myelodysplasia: "Who Should We Transplant Today?" LichtmanM ALeukemiaLeukemiaLichtman MA. Understanding the mutational evolution of clonal cytopenias and oligo...
This year, more than 1 million Americans and more than 10 million people worldwide are expected to be diagnosed with cancer, a disease commonly believed to
Potential therapeutic targeting of the osteo-hematopoetic niche The proposal of osteohematology provides a new concept of possible concurrent medical impact on both hematopoietic and stromal cells in MDS (and other diseases like multiple myeloma). One of the best examples of an osteo-hematological ...
Interestingly, it is also shown that Mastoparan amide (herein referred to as Mastoparan) clearly kills cancer cells by a lytic mechanism, which is in contrast to the non-amidated derivative [15]. Mastoparan was toxic to leukemia, myeloma, and breast cancer cells, and showed toxicity towards ...