Which immune cells of the adaptive immune system produce antibodies? What is the pathogenesis of autoimmune diseases? What makes an immune deficiency disorder so dangerous? What happens when the immune system fails? What is the dual nature of the adaptive immune system?
Defining an Immune System Disorder Lupus is an autoimmune disease affecting multiple organs and systems of the body. The causes and symptoms of lupus are far-ranging. But first, exactly what is lupus, and how is it best treated? What is lupus? It's a group of autoimmune diseases in which...
Multiple sclerosis (MS) is a neurodegenerative disorder caused by the immune system mistakenly attacking the myelin sheath, a protective coating around nerve fibers. This results in inflammation, which further damages the myelin sheath, as well as the nerve cells themselves and the cells that ...
An Allergy is a disorder of the immune systemAn Allergy is adisorderof theimmune system It is characterized by excessive activation of certainwhite blood cellscalledmast cellsandbasophilsby a type ofantibodyknown asIgE, resulting in an extremeinflammatoryresponse. these reactions areacquired, ...
Multiple sclerosis (MS) is an immune-mediated inflammatory and neurodegenerative disorder of the central nervous system (CNS). In MS, neuro-axonal loss is the major substrate of permanent clinical disability1and neuropathological studies indicate it is an early disease phenomenon2. In recent years...
TMEM10 expression in human MS plaques MS is an autoimmune disorder in which CNS myelin is attacked by the immune system. Although OPCs in the adult CNS are initially able to differentiate and remyelinate demyelinated regions, remyelination efficiency decreases as MS progresses, likely due to ...
Multiple sclerosis (MS) occurs as a result of an immune system attack on the surrounding myelin sheaths of neurons both in the brain and the spinal cord. This leads to poor communication between neurons and weakening of the axons. MS manifests as deteriorating physical ability and can also cau...
Lupus is an autoimmune condition that involves the body’s immune system mistakenly attacking parts of the body, including the skin.²⁶ Some forms of lupus can result in a “butterfly rash,” a red, raised rash across the nose and cheeks that can resemble a butterfly. Lupus needs to...
(ms) 1:800 dilution (Millipore Sigma); anti-GFAP (gt) 1:800 dilution (Novus Biological); anti-GFP 1:5,000 dilution (Thermo Fisher); anti-Hsp90 1:100 dilution (Abcam); anti-Iba1 (rbt) 1:300 dilution (Wako); anti-Iba1 (gt) 1:100 dilution (Abcam); anti-MBP 1:500 dilution (...
“diseases that regularly manifest without involvement of a common single system and with concomitant major involvement of several systems”, and, on this basis, a disorder such as rheumatoid arthritis would not be considered multisystem because, while it affects multiple systems, its predominant ...