Multiple sclerosis (MS) is an autoimmune disease that usually occurs during the reproductive years in both sexes. Many male patients with MS show lower blood testosterone levels, which was also observed in male rats during experimental autoimmune encephalomyelitis (EAE), an animal model of MS. To ...
TMEM10 expression in human MS plaques MS is an autoimmune disorder in which CNS myelin is attacked by the immune system. Although OPCs in the adult CNS are initially able to differentiate and remyelinate demyelinated regions, remyelination efficiency decreases as MS progresses, likely due to ...
Objective: Despite progress in treating relapsing multiple sclerosis (MS), effective inhibition of nonrelapsing progressive MS is an urgent, unmet, clinical need. Animal models of MS, such as experimental autoimmune encephalomyelitis (EAE), provide valuable tools to examine the mechanisms contributing ...
"Of course it gave me the 'I'm not a doctor, I can't diagnose you,'" Sarvela said. But then:multiple sclerosis. An autoimmune disease that attacks the central nervous system. Katie Sarvela. Katie Sarvela on Instagram Now 32, Sarvela started experiencing MS symptoms when she...
135. Willis MS, Patterson C. Into the heart: the emerging role of the ubiquitin-proteasome system. J Mol Cell Cardiol. 2006;41:567–79. 136. Xiao Y, Yin J, et al. Incidence and risk of cardiotoxicity associated with bortezomib in the treat- ment of cancer: a systematic review and ...
"Estriol didn’t help those with more advanced MS. Researchers hope that hormone may eventually be used to delay the progression into that advanced stage. In the meantime, women with MS can always get estriol the natural way, even if it’s only temporary." ...
[25,26] were accessed in April 2013. AITD, autoimmune thyroid disease; BD, Behcet’s disease; CD, celiac disease; IBD, inflammatory bowel disease; JRA, juvenile rheumatoid arthritis; KD, Kawasaki disease; MS, multiple sclerosis; PBC, primary biliary cirrhosis; PSC, primary sclerosing cholangitis...
uRM might be an autoimmune disease with high levels of anti-ENO1 antibodies in blood serum. The identification of ENO1 as a target for ATAB production enables us to search for a possible treatment of uRM in the future. 1. Introduction Recurrent miscarriages (RM) are defined as two or more...
Recent studies revealed an association between variants in PLD4 and two autoimmune diseases in human, namely systemic sclerosis [23] and rheumatoid arthritis [24], disorders with inflammatory skin lesions [25] and interstitial lung diseases [26, 27]. Furthermore, knock-out mice with a nonsense ...
The filters were washed and exposed to Kodak MS film using an MS intensifier screen at -70 °C for 2–72 h. Probes—Templates for human TNF-α and GAPDH probes were excised and gel purified from plasmids (pE4 and pHcGAP, respectively) obtained from ATCC. Coding sequences for human IRF...