Multiple sclerosis (MS) is an autoimmune disease that usually occurs during the reproductive years in both sexes. Many male patients with MS show lower blood testosterone levels, which was also observed in male rats during experimental autoimmune encephalomyelitis (EAE), an animal model of MS. To ...
MS is an autoimmune disorder in which CNS myelin is attacked by the immune system. Although OPCs in the adult CNS are initially able to differentiate and remyelinate demyelinated regions, remyelination efficiency decreases as MS progresses, likely due to impairment of OPC differentiation. Currentl...
Some types of diabetes are more challenging to diagnose, such as latent autoimmune diabetes in adults. A diabetes expert explains this relatively rare condition.
“The problem is because the concept of an autoimmune disease is quite new; the autoimmune diseases are treated by different physicians and in different departments and they’re not thought of generally as a single entity the way cancer is thought of or infectious diseases are thought of,” sai...
The Journal of Immunology, 1999, 162: 6247–6254. clinical, and immunological similarities between MS and an experimentally relapsing experimental 展开 年份: 1999 收藏 引用 批量引用 报错 分享 全部来源 求助全文 Semantic Scholar 相似文献Suppression of experimental autoimmune encephalomyelitis by oral ...
Objective: Despite progress in treating relapsing multiple sclerosis (MS), effective inhibition of nonrelapsing progressive MS is an urgent, unmet, clinical need. Animal models of MS, such as experimental autoimmune encephalomyelitis (EAE), provide valuable tools to examine the mechanisms contributing ...
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There has been an argument that AIRE-deficient mice are infertile due to autoimmune reasons and that a Recombination activating gene (RAG)-1-KO on AIRE-KO background was fertile since T/B lymphocytes were depleted in this model (42). However, these authors did not evaluate the effect of ...
(ms) 1:800 dilution (Millipore Sigma); anti-GFAP (gt) 1:800 dilution (Novus Biological); anti-GFP 1:5,000 dilution (Thermo Fisher); anti-Hsp90 1:100 dilution (Abcam); anti-Iba1 (rbt) 1:300 dilution (Wako); anti-Iba1 (gt) 1:100 dilution (Abcam); anti-MBP 1:500 dilution (...
[J]I've found that my handiwork with yarn has helped my arthritic (患关节炎的) fingers remain more dexterous (灵巧的) as I age. A woman encouraged to try knitting and crocheting after developing an autoimmune disease that caused a lot of hand pain ...