Numerous clinical studies have indicated, based on mortality rates, that methicillin-resistant Staphylococcus aureus (MRSA) strains are more virulent than methicillin-susceptible S. aureus (MSSA) strains. In contrast, quantitative laboratory examinations of the presence and magnitude of pathogenic mechanisms...
Is methicillin-resistant Staphylococcus aureus more virulent than methicillin-susceptible S. au- reus? A comparative cohort study of British patients with nosocomial in- fection and bacteremia. Clin Infect Dis. 2003;37:1453-60.Melzer M, Eykyn SJ, Chinn S. Is methicillin-resistant Staphylococcus ...
Persistent carriers had a more than 3-fold higher risk of all-cause CPD-related infections [incidence rate ratio (IRR) 3.52 (95% CI: 2.56–4.85)] and a more than 9-fold higher risk ofS. aureus CPD infections [IRR 9.54 (95% CI: 5.25–17.33)] compared to non– or intermittent ...
CONCLUSIONS: ST93-MRSA and CC121-MSSA are the dominant causes of carbuncles and furuncles in Central Australia. Both of these virulent clones harbor pvl but the impact on clinical outcomes remains uncertain. The high prevalence of CA-MRSA supports empiric vancomycin use in this population when ...
Our data showed that chp was present in more than 30% of S aureus strains. Of note, more than 30% of MSSA was PCR-positive for chp. Production and characteristics of recombinant CHIPS A truncated version of CHIPS that did not contain a signal sequence at the N-terminus showed a similar...
In an embodiment, the microorganism is a methicillin resistantS. aureus(MRSA). In an embodiment, the C-terminal residue is amidated. In an embodiment, the peptide has an amino acid sequence of SEQ ID NO: 29. In an embodiment, the peptide comprises one or more D-amino acids, optionally ...