But similar clinical picture can be seen in various disorders right from degenerative illnesses like motor neuron disease to inflammatory ones like multifocal motor neuropathy (MMN). Some of them are potentially treatable conditions with immunomodulatory therapies and are associated with characteristic ...
Differential diagnosis between multifocal motor neuropathy and motor neuron disease (MND) is important. In case of slowly progressive asymmetrical flaccid quadriparesis MMN should always be taken in account. Electrophysiological and other supportive diagnostic tests should be performed. Also in case of ...
SSA refers to the selective attenuation of responses to repeated (common) stimuli and can be seen as a single-cell analog of MMN (Ulanovsky et al., 2003). Although their exact relation remains debated, SSA is probably not a direct substrate of MMN, since the phenomena differ in latencies,...
Interpretation MMN susceptibility is associated with a 21-bp deletion in the CD55 promotor region (rs2871582), which is associated with lower CD55 expression. Patients carrying this deletion may have a more favorable long-term disease outcome. Taken together, these results point out the...
Exercise-induced adult hippocampal neurogenesis was associated with increases in both Fndc5 and Bdnf genes, thus improving cognition in a mouse model of Alzheimer's disease [90]. Then, stroke is associated with a strong neuroinflammation that affects neuroplasticity processes within the core of lesion...