In the clinical study, we confirmed a moderate induction of CYP2B6 (decrease in the efavirenz AUC by 79%) and 3A4 (decrease in the midazolam AUC by 68%) by metamizole. In addition, metamizole weakly induced CYP2C9 (decrease in the flurbiprofen AUC by 22%) and moderately CYP2C19 (...
(0.91 to 1.06) (0.91 to 1.07) Midazolam 25 mg 10 _ 0.95 _ 3 mg once daily (0.79 to 1.15) Norelgestromin 50 mg 15 0.89 0.98 0.93 0.25 mg twice daily (0.82 to 0.97) (0.91 to 1.04) (0.85 to 1.03) a The number of subjects represents the maximum number of subjects that were ...
dexmedetomidine (0.25 μg kg–1minute–1) and halothane, DEX + ISO group received an intravenous continuous infusion of dexmedetomidine (0.25 μg kg–1 minute–1) and isoflurane, MID + HAL group received an intravenous bolus of midazolam (1 mg kg–1) and halothane, ...
Because an increase in central serotonergic ... K Semba,N Adachi,T Arai - 《Anesthesiology》 被引量: 123发表: 2005年 A randomized controlled trial on use of propofol alone versus propofol with midazolam, ketamine, and pentazocine "sedato-analgesic cocktail" for sedation d... Background and ...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook INO (redirected fromInhaled Nitrous Oxide) AcronymDefinition INOInoperative INOInstitut National d'Optique(in Sainte-Foy, Quebec, Canada) INOInternuclear Ophthalmoplegia ...
General anaesthesia was induced with midazolam (0.1 mg/kg), fentanyl (4 μg/kg) and propofol (1–2 mg/kg). Cisatracurium infusion (0.15 mg/kg) was used to facilitate tracheal intubation and obtain intraoperative muscle relaxation. Anaesthesia was maintained with oxygen in air (1:2), ...
Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients: a systematic review. Patients in Intensive Care Unit (ICU) often require sedatives which commonly include midazolam and the more recently developed α2-receptor agonist, dexmed... Adams,R.,Brown,......
Mice were anesthetized by intraperitoneal injection of a mixture of midazolam (5.0 mg/kg body weight [BW]), medetomidine (0.5 mg/kg BW), and fentanyl (0.05 mg/kg BW). A midline laparotomy incision was made and the IVC was exposed immediately below the renal veins. A 5-0 Prolene suture...
1 a Plasma concentrations and effect in a 2-year-old child given protocol midazolam bolus (0.1 mg/kg) and infusion changes (100 lg/kg/h step changes) every 30 min to achieve sedation. Infusion was stopped at 180 min. Sedation recovery lags behind the decline in plasma concentration. ...
The Influence of Single-Dose and Short-Term Administration of Quercetin on the Pharmacokinetics of Midazolam in Humans Quercetin is a plant flavonol that is available from both daily diet and nutraceuticals. To investigate the effect of acute and short-term intake of high-d... AN Mai,P Staubac...