Lithium bis(trimethylsilyl)amide is a non-nucleophilic strong Brønsted base, which is generally soluble in most of the nonpolar organic solvents. It is most commonly employed in organic reactions. It is used as the base employed in generating enolates for the preparation of lactone precursors, ...
A good nucleophile is a good Lewis base. This means that it is able to donate an electron pair. The factor that we can... Learn more about this topic: Nucleophile | Definition, Reactions & Examples from Chapter 4/ Lesson 18 37K
<p>To determine which among the given options is not a nucleophile, we need to analyze the electron-rich species and their ability to donate electrons. A nucleophile is defined as a species that is electron-rich and can donate an electron pair to an elec
A halogenation addition reaction with an acid and an alkene produces a halogenated hydrocarbon in the place of the carbon-carbon double bond. The...
Poprezinc is a new anti-ulcer drug developed by Japan's Hamari New Drug Co., Ltd. It is the first zinc-containing compound for clinical use. The drug was launched in Japan in 1994 under the trade name Promac in the form of granules. agent. Polaprezinc is a Polaprezinc complex. L-...
Commercially available alkali metal bases which are readily attainable are presently preferred, such as sodium hydroxide, potassium hydroxide, lithium hydroxide, sodium methoxide, etc. Currently, it is preferred that anhydrous sodium hydroxide be employed to provide the strong basic reaction environment ...
Many drugs bind to and activate human pregnane X receptor (hPXR) to upregulate drug-metabolizing enzymes, resulting in decreased drug efficacy and increased resistance. This suggests that hPXR antagonists have therapeutic value. Here we report that SPA70
Retinol binding protein 4 (RBP4) facilitates the transport of retinol in the body but is also an adipokine and fatty acid transporter. Our study was aimed at investigating the associations between RBP4 abundance and fat deposition in cattle. Blood sample
The base may optionally be derived by the addition of an alkali metal to a lower-aliphatic alcohol. In some particular embodiments, the metal is selected from sodium, potassium, lithium and magnesium. In more particular embodiments, the alkoxide is selected from methoxide, ethoxide, i-propoxide,...