Diabetes mellitus (DM) is a metabolic disease that activates several molecular pathways involved in neurodegenerative disorders. Metformin, an anti-hyperglycemic drug used for treating DM, has the potential to exert a significant neuroprotective role against the detrimental effects of DM. This review ...
Metformin-associated lactic acidosis: Current perspectives on causes and risk Although metformin has become a drug of choice for the treatment of type 2 diabetes mellitus, some patients may not receive it owing to the risk of lactic ... Ralph DeFronzo a,G. Alexander Fleming b,Kim Chen c,.....
The role of metformin (MET) in the treatment of patients with advanced HFrEF and type 2 diabetes mellitus (DM) is not firmly established. We studied the impact of MET on metabolic profile, quality of life (QoL) and survival in these patients. A total of 847 stable patients with advanced ...
BACKGROUND: Several epidemiological studies have shown a positive association between diabetes and increased risk of non-Hodgkin lymphoma (NHL), but the effect of diabetic treatment drugs such as metformin on the risk is unknown. METHODS: We conducted a population-based nested case-control study inv...
"Diabetes is prevalent, but pre-diabetes is even more prevalent and we have evidence-based therapies like metformin that are very safe and that work," Moin said. "Metformin is rarely being used fordiabetes preventionamong people at risk for developing it. This is something that patients and do...
Hello everyone out there, I'm getting the impression that long-term use of metformin can cause kidney failure. Is it true? What I'm hearing is that people with type 2 diabetes are better to inject insulin than take metformin because of metformins ability to cause kidney damage. I happen ...
摘要: Diabetes Metab. 2003 Sep;29(4 Pt 2):6S5-7. Editorial; Review 关键词: Humans Arteriosclerosis Cardiovascular Diseases Diabetes Mellitus, Type 2 Glucose Intolerance Insulin Resistance Metabolic Syndrome X Metformin Hypoglycemic Agents DOI: 10.1016/S1262-3636(03)72782-7 被引量: 34 年份...
Al Hilli MM, Bakkum-Gamez JN, Mariani A, Cliby WA, Mc Gree ME, Weaver AL, Dowdy SC and Podratz KC: The effect of diabetes and metformin on clinical outcomes is negligible in risk-adjusted endometrial cancer cohorts. Gynecol Oncol 140: 270-276, 2016....
Metformin use in patients with type 2 diabetes mellitus is associated with reduced risk of deep vein thrombosis:a non-randomized,pair-matched cohort study... Lu, Dai-Yin,Huang, Chin-Chou,Huang, Po-Hsun,... - 《Bmc Cardiovascular Disorders》 被引量: 14发表: 2014年 Author's response to re...
Metformin, an insulin-sensitizer, may correct several physiologic abnormalities owing to insulin resistance in patients with type 2 diabetes mellitus (DM). The effects of metformin on venous thrombosis in patient with type 2 DM have not been reported. Our study strived to explore the relationship ...