First step in phagocytosis, or “cell eating” a macrophage extends several pseudopods from it’s singlecelled form to embrace a number of E-coli bacteria. 吞噬作用的第一步,即“细胞吞噬”,巨噬细胞从单细胞形态中延伸出几个假足,以容纳大量的大肠杆菌。这是巨噬细胞,不是NK细胞。 Bacteria trapped...
( 1981 ) Macrophage or T cell: that is the question . Immunol. Today 2 , 228 .Nagy, ZA, Klein, J (1981) The expression of Ir genes: macrophage or T cell — that is the question. Immunology Today 2: pp. 228-229Nagy, Z.A. and Klein, J.: Macrophage or T cell-that is the ...
Ly-6C- cultured monocytes and Ly-6C- monocyte-like cell lines, but not fully differentiated macrophages and macrophage-like cell lines, can be induced to express the Ly-6C antigen by interferon-gamma. A population of small vessel endothelial cells in diverse tissues also express high levels of...
Interestingly, infected monocyte–macrophage populations persisted in spleen and BM tissues and were readily detected even considering rates of human cell reconstitutions. These findings, taken together, provide a model for future investigations that seek to target the ultimate elimination of the viral ...
Patients from three tislelizumab monotherapy trials in solid tumors (NCT02407990, NCT04068519, NCT04004221) were retrospectively divided into subgroups by CD8+ T-cell and macrophage (Mφ) levels, assessed via multiplex immunohistochemistry (mIHC; n = 67) or gene expression profiling (GEP; n...
Macrophage-T cell interaction is essential for the induction of p75 interleukin 2 (IL-2) receptor and IL-2 responsiveness in human CD4+ T cells. Jpn J Cancer Res. 1991 Mar; 82 (3):257–261.Nakamura Y,Nishimura T,Tokuda Y,et al.Macrophage-T cell interaction is essential for the ...
Approaches to characterize cell types Cell types are the product of evolution Hierarchical organization of transcriptomically defined cell types Correspondence between transcriptomic cell types and other cellular properties Cell types versus cell states Cell type development How to define cell types? Acknowled...
This overexpression fosters BC cell proliferation, migration, EMT, and resistance to PAX chemotherapy by driving M2-like macrophage polarization. HCG18 promotes M2-like TAMs polarization by impacting the miR-365a-3p/ forkhead box-1(FoxO1)/CSF-1 axis, which in turn enhances cetuximab resistance in...
(Fig.4a–d). After phagocytosis by macrophages,atp16Δ/Δ was locked in only the spore form, with a significant reduction in theC. albicanssurvival rate and macrophage cell damage compared with that of WT, which formed hyphae and escaped from macrophages (Fig.4e–g). As phagocytes are ...
Using granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 we have established dendritic cell (DC) lines from blood mononuclear cells that maintain the antigen capturing and processing capacity characteristic of im... F Sallusto,A Lanzavecchia - 《Journal of Experimental Medicine...