The concentrations of RNA were determined using a spectrophotometer, and molecule integrity was checked by gel electrophoresis. The quality of RNA was confirmed using an Agilent 2100 Bioanalyzer (Agilent Technologies, Santa Clara, CA, USA). The miRNA expression signatures and data normalisation The ...
The first and second cleavage yields a heavy chain (64 kd) joined by a single disulfide bond to a light chain (56 kd) and release of BK. The third cleavage occurs later and proteolyzes the 56-kd light chain to a 45-kd light chain and this two-chain molecule has been termed HKa. ...
Highly-abundant peptide peaks derived from entire mAb molecule sequence are reflected in the chromatogram of ProAlanase-digested mAb (Fig. 6A), whereas only a few abundant peptide peaks, covering the heavy chain Fc region, are observed in the tryptic chromatogram (Fig. 6B). This is likely ...
Does diacylglycerol serve as a signaling molecule in plants? Plant Signal Behav. 2012;7:472–5. 80. Stergiopoulos I, de Wit PJGM. Fungal effector proteins. Annu Rev Phytopathol. 2009;47:233–63. 81. Bauer R, Oberwinkler F, Vanky K. Ultrastructural markers and systematics in smut fungi ...
Through quantitative live-cell imaging, we show that TauC3 has a drastically reduced dynamics of its microtubule interaction. Single-molecule tracking of tau confirmed that TauC3 has a longer residence time on axonal microtubules. The reduced dynamics of the TauC3-microtubule interaction correlated ...
A recombinant soluble form of the IL-11Rα (sIL-11Rα) in combination with IL-11 acts as an agonist on cells expressing the gp130 molecule. We constructed a designer cytokine Hyper IL-11 (H11), which is exclusively composed of naturally existing components. It contains the full length ...
Hydrogen sulfide (H2S) is gaining acceptance as a signaling molecule and has been shown to elicit a variety of biological effects at concentrations between... KR Olson - 《Biochimica Et Biophysica Acta Bioenergetics》 被引量: 439发表: 2009年 Hot Gas Removal of Tars, Ammonia, and Hydrogen Sulfi...
Together, our studies demonstrated that a fundamental molecule, ATP could be recognized as a potent regulator and/or modulator of angiogenesis in microvascular endothelial cells. 展开 DOI: 10.1096/fasebj.22.1_supplement.49.8 年份: 1973 收藏 引用 批量引用 报错 分享 ...
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Ubiquitin: same molecule, different degradation pathways. Cell. 2010;143:682–5. Article CAS PubMed Google Scholar Shi D, Grossman SR. Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets. Cancer Biol Ther. ...