muridarum. Mice anaesthetized with ketamine (Parnell Laboratory, Sydney, Australia; 100 mg kg À 1)/xylazine (Bayer, Lever- kusen, Germany; 10 mg kg À 1) were challenged intravaginally with C. muridarum in 20 ml of SPG two weeks following immunization. Mice recovering from a primary ...
. Twenty-four hours later, the mice were euthanized by cervical dislocation under anesthesia with a mixture of ketamine (100 mg/kg)/xylazine (5 mg/kg, i.p., Sigma, Oakville, Ontario, Canada) after ensuring that they did not respond to a needle prick of the skin. The hearts were ...
Athymic female mice (6–8 weeks old) were anesthetized with ketamine/xylazine and administered a preoperative dose of buprenorphine prior to stereotactic intracranial injection. Each mouse was injected with 200,000 cells in a volume of 2 uL 3 mm deep, 1 mm to the right of the sagittal...
injection of ketamine (100 mg/kg, Vetlar V, Pfizer, Kent, UK) and xylazine hydrochloride (10 mg/kg, Xylacare, Animalcare, York, UK) delivered in 0.9% saline solution. The trachea and right common carotid artery were cannulated and the liver was exposed. Prior to ischemia, 250 μl of...
a recent report, pretreatment with ketamine blocked the development of depressive-like behavior in mice as a result of administration of lipopolysaccharide, a potent activator of the inflammatory response.35Surprisingly, ketamine had no effect on lipopolysaccharide-induced inflammatory activation in the brai...
Under ketamine-xylazine anaesthesia (60 + 1 0 mg/kg, i.p.), each rat was implanted surgically with a plastic guide cannula (Linca, Tel-Aviv, Israel), stereotaxically inserted through a skull hole drilled over the left lateral ventricle of the brain (1 mm caudal to and 1.8...
Vestibular evoked potentials. For VsEP testing, mice were anesthetized with a solution containing ketamine (18 mg/ml) and xylazine (2 mg/ml), using 5–9 μl per gram body weight injected intraperitoneally. Core body temperature was maintained at 37.0 ± 0.1 °C. ...
Some animals were anaesthetized with ketamine (100 mg kg À 1 i.p.) mixed with xylazine (10 mg kg À 1 i.p.). Thirty minutes prior to anaesthesia, 60 mg kg À 1 pimonidazole (HPI Inc., Burlington, USA) was injected i.p. to mark hypoxic areas in the tumours. Fifty mg of ...
injection using a mixture of 4.12 ml saline (NaCl), 0.38 ml Ketaset (containing 100 mg ml − 1 ketamine) and 0.5 ml Domitor (containing 1 mg ml − 1 medetomidine hydrochloride) administered at 0.1 ml per 10 g body weight. In addition 0.01 ml Rimadyl (5 mg kg − 1 Carprofen) ...
Mice were anesthetized with ketamine (Putney Inc., Portland, ME; 100 mg/kg i.p.) and xylazine (Akorn Inc., Lake Forest, IL; 10 mg/kg i.p.). Supplemental injections at 1/3-1/2 of the original dose were administered if needed. Animals were placed on a temperature-controlled (37...