We demonstrate that ADI, derived from a dairy-Generally Recognized As Safe (GRAS) strain of L. lactis, exhibits anti-proliferative activity on cell lines with different levels of argininosuccinate synthetase 1 (ASS1) expression. A unique feature of the Lc4 strain is also its capability to ...
Arginine kinaseDrosophila melanogasterShort-term memoryMushroom bodies are a higher order center for sensory integration, learning and memory of the insect brain. Memory is generally subdivided into different phases. In the model organism Drosophila melanogaster, mushroom bodies have been shown to play a...
While refillable drug-eluting depots may hold promise as a long-term solution, the blood-brain barrier (BBB) presents a major barrier to successful drug refills reaching the brain. In mice, this article highlights the non-invasive, focused ultrasound-mediated loading of intracranial drug depots....
In addition, it’s been found that arginineboosts the body’s abilityto make proteins, which is important for repairing muscle tissue, treating wounds, sparing tissue wasting, boosting the metabolism, and aiding in proper growth and development. ...
You gain quick access to your desire and then pay for it in other ways, such as side effects which can be detrimental to your long-term health. Synthetic substances like injections always seem to work in the short term but don’t pan out over time. Supplements are a safer alternative to...
However, because all of the above methods originate from synthetic chemicals or other organisms and may have long-term toxicity or other side effects, which limit their clinical applications in humans, further improvements are needed to obtain a safe, efficient system for drug delivery into the ...
Proteins have existed on earth for billions of years and are the primary building blocks of most forms of life, from the simplest bacteria to the most sophisticated life forms. In fact, it isn't really a thing, as much as it is a category of things. There are millions of different type...
The application of phages is a promising tool to reduce the number of Campylobacter along the food chain. Besides the efficacy against a broad range of strains, phages have to be safe in terms of their genomes. Thus far, no genes with pathogenic potential (e.g., genes encoding virulence fa...
It operates by converting the amino acid arginine into nitric oxide and citrulline using oxygen and NADPH. The generated NO has vasodilatory properties and plays a role in the body’s immune response to infections and inflammation [25]. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor...
decrease the growth of tumor cells in laboratory cultures and inhibit tumor development in living organisms [41,42,43]. It is proposed that carnosine accumulation restricts glycolysis, thereby limiting energy production [43]. Moreover, carnosine has been observed to reduce the production of cellular...