A very important open question in stem cells regulation is how the fine balance between GSCs self-renewal and differentiation is orchestrated at the molecular level. In the past several years much progress has been made in understanding the molecular mec
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So far, due to its clinical importance—as connected to the multidrug resistance—a non-selective transporter HsABCG2 is one of the most studied proteins from the G subfamily. Obtained HsABCG2 cryo-EM data provide some structure–function insights. For instance, it enabled for the identificatio...
This is because a very short window implies that there are risks of missing the full market reaction, as it may take time for the market to evaluate the news. On the other hand, if a very long window is chosen, the risks are that the estimated reaction can be contaminated by other ...