potentially indicating neuro-inflammatory activity. Assessing peripheral cytokines in an adult population with ADHD is also very important for treating comorbid mental disorders such as depression
Polygenic risk for ADHD was associated with age 11 IQ in the LBC1936 cohort; however, in contrast to ASD, greater polygenic load was negatively correlated with IQ (beta = − 0.09, P = 0.004). This result was not replicated in LBC1921. A meta-analysis of the LBC1921 and LBC1936 ...
Asymptomatic sterile intra-amniotic inflammation in the mid-trimester of pregnancy, followed by a term birth, can still confer to the offspring a substantial risk for neurodevelopmental disorders in childhood. Early recognition and treatment of maternal immune activation in pregnancy may be a strategy f...
In both the autism and con- trol groups, performance on each expression recognition task was moderately correlated with verbal, performance, and full-scale IQ (autism r's: 0.34–0.53, control group r's: 0.24–0.44, all p < 0.001). Age was weakly correlated with accuracy on the KDEF...
Finally, proxies may also be associ- ated with cognitive decline via mechanisms other than reserve [35]. For instance, greater educational attainment is correlated with higher socioeconomic status [36] which is itself associated with slower cognitive decline [37] and reduced risk and prevalence of...
(BMI, kg/m2) in a large sample of elderly men and women from Tromsø, Norway. Methods: In a cross-sectional survey, with 1558 men and 1553 women aged 65 to 87 years, the risk of malnutrition was assessed by the Malnutrition Universal Screening Tool (’MUST’), and mental health was...
correlated to frontal WM volume (r 0.4, p = 0.003) and frontal grey matter volume (r 0.3, p = 0.01) [49]. However total WMH burden was not associated with gait speed. It is not exactly clear why they looked at frontal brain volumes and gait speed and not other regions of...
Arguably the most developed is based on the notion of complexity, and the observation that performances on tasks, occupations, and work that are more complex, broadly defined, tend to be more highly correlated with intelligence. The ensuing supposition is that intelligence entails a capacity to ...
In the case of AD, the only CSF amino acid that significantly correlated with insulinemia was arginine. This correlation may be explained by the hyperinsulinemia-induced upregulation of brain arginase activity, as observed in obesity [109]. Increased arginase activity consumes arginine and reduces ...
Such measurements undertaken at age 11 were later shown to be correlated with a large number of health outcomes in later life, with higher scores on a range of psychometric testing increasing the odds of surviving past 79 years [80]. Similarly, the decline in psychometric scores that occurs ...