Tricyclics include imipramine (Tofranil®), which is prescribed for panic disorder and GAD, and clomipramine (Anafranil®), which is the only tricyclic antidepressant useful for treating OCD. Monoamine oxidase inhibitors (MAOIs) are the oldest class of antidepressant medications. The MAOIs most ...
We examined the relationship between the Arg16Gly polymorphism of beta2-adrenoceptor (ADRB2) and the efficacy of tricyclic antidepressant therapy in patients with interstitial cystitis (IC). We studied 55 IC patients and 113 controls. The IC patients were treated with imipramine hydrochloride, and ...
The aim of the present study was to investigate the influence of tricyclic antidepressants (TADs: imipramine, amitriptyline, clomipramine, and desipramine), selective serotonin reuptake inhibitors (SSRIs: fluoxetine and sertraline) and novel antidepressant drugs (mirtazapine and nefazodone) on the ...
A history of urinary retention Coronary artery disease(CAD) Liver disease Top TCAs to treat depression TCAs in the U.S. include: Amitriptyline (Elavil) Amoxapine (Asendin) Desipramine (Norpramin) Doxepin (Sinequan) Imipramine (Tofranil) ...
Hypericum perforatum (St John's wort) is therapeutically equivalent to the tricyclic antidepressant imipramine in treating patients with mild to moderate depression. On page 536 Woelk reports the results of the largest randomised, multicentre, double blind trial to compare hypericum with a tricyclic...
Imipramine (Tofranil). This tricyclic antidepressant is FDA-approved for depression and as an add-on therapy for nighttime bedwetting in kids older than 6. It may be used off-label for chronic nerve pain and panic disorder. Nortriptyline (Pamelor). This tricyclic antidepressant is FDA-approved ...
In this study, we examined the acute effects of sertraline, a selective serotonin reuptake inhibitor (SSRI) and imipramine, a tricyclic antidepressant (TCA) on the endocrine endpoints, adrenocorticotropin (ACTH) and cortisol secretion in gonadectomised male and female sheep. Each sheep was treated...
Amitriptyline, a frequently prescribed tricyclic antidepressant, isreported to produce an age-related impairment in anterograde memory. However, the locus of this adverse effect has never been described within the context of contemporary learning and memory theory. ...
Clinical findings on the effects of antidepressant use on body weight TCA In the study conducted by Berkenet al., low to moderate doses of the TCAs amitriptyline (150 mg per day), nortriptyline (50 mg per day) and imipramine (80 mg per day) were associated with a mean weight gai...
All drugs completely inhibited the OCT1-mediated uptake of morphine in a concentration-dependent manner (Fig. 4). The potency of the drugs as inhibitors varied between IC50 of 1.2 ± 0.2 μM (ondansetron) to 6.2 ± 1.4 (imipramine). The observed IC50 values for inhibition of morphine uptake...