Is IL-6 the best pro- inflammatory biomarker of clinical outcomes of cancer cachexia? Clin Nutr. 2012; 31(1):85-88.Scheede-Bergdahl C, Watt HL, Trutschnigg B, Kilgour RD, Haggarty A, Lucar E, et al. Is IL-6 the best pro-inflammatory biomarker of clinical outcomes of cancer ...
In addition to local inflammation of the joints, patients are associated with systemic inflammatory manifestations such as fever, fatigue and anemia, and laboratory findings such as elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), hyper-纬-globulinemia, and thrombocytosis....
Thus, we performed Reverse Phase Protein Array (RPPA) analysis for pJAK1 in SMARCB1 KO compared with control and SMARCB1 rescue spheroids, and the results revealed a significant increase in pJAK1 levels in SMARCB1 KO spheroids (Supplementary Fig. 9D). We subsequently measured the IL6 levels ...
Although IL-6 is elevated in malignant gliomas, and glioma cells respond to IL-6, its functional role in gliomagenesis is unclear. We have investigated this role of IL-6 in a mouse model of spontaneous astrocytoma by crossbreeding glial fibrillary acidic protein (GFAP)-viral src oncogene ...
Although IL-6 is elevated in malignant gliomas, and glioma cells respond to IL-6, its functional role in gliomagenesis is unclear. We have investigated this role of IL-6 in a mouse model of spontaneous astrocytoma by crossbreeding glial fibrillary acidic protein (GFAP)-viral src oncogene ...
常见的免疫检查点包括细胞毒性T淋巴细胞相关抗原(cytotoxic T Lymphocyte associated protein 4,CTLA-4) 和程序性死亡受体-1 (programmed death-1,PD-1)。CTLA-4作用于免疫应答的起始阶段,能够降低T细胞的活化;PD-1一般作用于免疫应答的效应阶段,PD-1与程序性死亡配体-1 (programmed death ligand-1,PD-L1)结合,...
Don't already have a personal account? Register DNA damage repair enzyme APE1 is a non-classical secretory protein and acts as a mediator of IL6 dependent inflammatory responses (IRM11P.626) - 24 Hours access EUR €34.00 GBP £28.00 USD $38.00 Citation...
(7% O2, light and dark blue bars, respectively;n = 6 biologically independent samples).BWestern blot images of protein bands from (A). Data are mean ± SEM. Asterisks indicate significant difference from normoxic controls (one-way ANOVA with Tukey multiple comparisons test; F2,15 ...
TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes. FEBS Lett. 1994 Jul 25; 349 (1):45–49.Roeb E, Graeve L, Mullberg J, Matern S and Rose-John S: TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes....
Peak KC proliferation was impaired in Il6-knockout (KO) mice and restored after the administration of IL-6 protein, whereas KC proliferation was not affected in Il4-KO or Csf2-KO mice. The source of IL-6 was identified using hepatocyte- and myeloid-specific Il6-KO mice and the results...