The mutations in claudin 1 gene were reported to cause a recessive neonatal ichthyosis sclerosing cholangitis syndrome, in which a bile leakage through tight junctions of hepatocellular and biliary cells was found37. Claudin 2 deficiency altered paracellular permeability required for proper regulation of ...
Bovine hereditary zinc deficiency (BHZD) is an autosomal recessive disorder of cattle, first described in Holstein-Friesian animals. Affected calves suffer from severe skin lesions and show a poor general health status. Recently, eight calves with the phenotypic appearance of BHZD have been reported ...
Cutaneous mosaicism, in KRT1 pI479T patient, caused by the somatic loss of the wild‐type allele, leads to the increase in local severity of the disease Background Epidermolytic ichthyosis (BCIE, OMIM 113800), is an autosomal dominant disorder of the skin caused by mutations in keratin genes ...
Skin disease is an illness of the skin, such as a bacterial or fungal infection, a cancer, or an allergic reaction. Some skin...
When your hands lose moisture, the skin becomes dry and can crack.Aging, eczema and an inherited condition called ichthyosis all cause dry, cracked skin.Such environmental conditions as cold, dry air also can irritate your exposed skin.Older individuals who have suffered an injury also may find...