(2005) Is Hypercholesterolemia a Risk Factor for Alzheimer’s Disease? Molecular Neurobiology, 31, 185-192.Wood WG, Igbavboa U, Eckert GP, Johnson-Anuna LN, Muller WE (2005) Is hypercholesterolemia a risk factor for Alzheimer’s disease? Mol Neurobiol 31:185–192...
A lipid profile test, which measures the amount of total cholesterol, triglycerides, HDL and LDL in the blood, is often needed for the diagnosis of hyperlipoproteinemia. Cardiologists, doctors who specialize in heart and blood vessel problems, usually treat the disease with medications known to ...
As an autosomal dominant disorder, familial hypercholesterolemia (FH) is mainlyattributed to disease-causing variants in the low-density lipoprotein receptor (LDLR) gene. The aim of this study was to explore the molecular mechanism ofLDLRc.501C>A variant in FH and assess the efficacy of proprotei...
Hypocholesterolemia is a condition in which a person doesn't have enough blood cholesterol. It's typically found in people who...
The pathway for the transport of cholesterol in blood and its receptor-mediated endocytosis by target tissues was elucidated by Michael Brown and Joseph Goldstein.;They discovered that individuals with the genetic disease familial hypercholesterolemia (FH) have mutations in the LDL receptor that pr the...
Hypercholesterolemia(high blood cholesterol) is common in Nephrotic Syndrome. In addition to albumin, other important enzymes involved in cholesterol metabolism, slip through the glomeruli, which contribute to high blood cholesterol. How common is the condition… ...
4 ⅐ No. 3 Hypercholesterolemia in children with Smith- Magenis syndrome: del (17)(p11.2p11.2) Ann C.M. Smith, MA, DSc(Hon)1–3, Andrea L. Gropman, MD1, Joan E. Bailey-Wilson, PhD4, Ozlem Goker-Alpan, MD1, Sarah H. Elsea, PhD5, Jan Blancato, PhD3, James R. Lupski, ...
Hypercholesterolemia is the leading risk factor for cardiovascular diseases. Current evidence suggests that the heritability for blood cholesterol levels is high, with 40%–60% in different cohorts.1,2 Genome-wide association study (GWAS) is a powerful tool to ascertain the contribution of common gen...
My father has hypercholesterolemia (or simply -elevated blood levels of cholesterol). I read something more about this condition and I found that people with hypercholesterolemia have a much higher tendency to develop the ischemic heart disease. Please, can somebody give me information how to treat...
What genetic mutation causes hypercholesterolemia? What chromosome does neurofibromatosis affect? What is caused by an autosomal dominant mutation? What is the genetic inheritance pattern of Down syndrome? What is the relationship between genetic drift and disease?