a AA represents homozygous, AB represents heterozygous, and BB represents homozygous alternative. b The ancestral A haplotype accumulates SNPs, differentiating it into two versions of the A haplotype: A1 and A2. The ‘Y’ shaped haplotype tree represents the predicted evolutionary relationships between...
When a genotype is homozygous dominant, it means that it has two dominant alleles for a particular genetic trait. If a parent is...
Differences in allele, genotype, haplotype, and haplotype combination distribution between the groups were examined by chi(2) test. Distributions of alleles, genotypes, and haplotypes at three loci defined by examined SNPs were not significantly different between the groups. However, the homozygote ...
Profile alignment for a portion of the N-terminal region (Muspositions 105–125 a.a.) of HOXD13 inPeromyscus, other rodents and human.f, Left: examples of transgenicMuswild type and homozygous for the engineeredHoxd13CRISPR
A Homozygous Genetic Variant of Mitochondrial Uncoupling Protein 4 Exerts Protection Against the Occurrence of Multiple Sclerosis[J] . Zoltan Szolnoki,Andras Kondacs,Yvette Mandi,Anita Bodor,Ferenc Somogyvari.NeuroMolecular Medicine . 2009 (2)Zoltan Szolnoki,Andras Kondacs,Yvette Mandi,Anita Bodor,Ferenc...
The homozygous fcgammarIIIa-158v genotype is a risk factor for heparin-induced thrombocytopenia in patients with antibodies to heparin-platelet factor 4 complexes. Blood. 2004;104(9):2791-2793.Gruel Y, Pouplard C, Lasne D, Magdelaine-Beuzelin C, Charroing C, Watier H (2004) The ...
We have shown previously that a variant allele of the short-chain acyl-CoA dehydrogenase ( SCAD ) gene, 625G-->A, is present in homozygous form in 7% of control individuals and in 60% of 135 patients with elevated urinary excretion of et... G Niels,VS Winter,MJ Corydon,... - 《Hum...
The CYP19(TTTA)(n) polymorphism was genotyped.The mean age at menarche was 12.9 ± 1.2 years and the BMI = 19.8 ± 2.3 kg/m(2). Genotype analysis revealed 5 CYP19(TTTA)(n) alleles containing 7-11 TTTA repeats. Girls homozygous for the allele with 7 TTTA repeats had earlier ...
Sanger sequencing of the ALPL variant revealed all seven puppies to be homozygous for the missense change (Fig. 3). Furthermore, all dogs from a cohort 281 control KBDs were either heterozygous or wild-type dogs. We then used a Taqman assay to genotype an additional set of 221 unaffected...
When combining data from single-sample calls, a no call at a particular site in a particular sample was deemed as a homozygous reference genotype if the depth at that site in that sample was greater than ten and missing otherwise. Lastly, we applied the site-level filters to exclude variants...