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A central region of TNIP2 interacted with the endosomal sorting complex ESCRT-I via its TSG101 subunit, a protein essential for HIV-1 budding, and a single point mutant in TNIP2 disrupted this interaction. The major gene ontology category for TNIP2 associated proteins was mRNA metabolism, and...
sgRNAs were identified by deep sequencing and filtered based on fold change and subcellular localization of the corresponding protein (Fig. 1b). Fig. 1: CRISPR activation screen identifies PirB as a potential host receptor for reovirus. a Schematic of CRISPRa screening methodology. ① JAM-A−...
Protein Profile of Blood Monocytes is Altered in HTLV-1 Infected Patients: Implications for HAM/TSP DiseaseJuliana LimaDenise PereiraThais Silva de OliveiraRussolina Zingali
CMs are the main postprandial source of TGs for peripheral cells and tissues.4, 5, 6 In addition to the master transcription factor sterol regulatory-element binding protein (SREBP) that governs lipid metabolism, CREB-H is another ER membrane-bound transcription factor pivotally involved in the ...
The protein sources (casein and L-cystine) were consistent across diets, as were sources of carbohydrate (cornstarch, maltodextrin, sucrose). Additionally, the type and amount of polysaccharide (cellulose) were comparable between diets. The source of fat (soybean oil for AIN-93M versus soybean ...
Dermer and Ham –Ethylenimine and other aziridines Dodd –The ACS Style Guide Feibelman –A PhD Is Not Enough!(Loaned out) Fieser – Reagents for Organic Synthesis (vol 1) Greene and Wuts –Protective Groups in Organic Chemistry Hammesfahr and Stong –Creative grass blowing ...
Several models have been put forward to explain how the pressure of fast evolving pathogens drives MHC diversity, for example balancing selection, over dominant selection and rare allele advantage All these models are reviewed and discussed in a recent review by Jeffery and Bagham [42]. coding ...
Our finding provides the first evidence that SUMOylation at the N-terminal α-amino group of a protein, rather than the internal lysine(s), is essential and sufficient for controlling the protein’s key function. Results CFL1 is modified by SUMO1 in vivo and in vitro To test whether CFL...
Protein Profile of Blood Monocytes is Altered in HTLV-1 Infected Patients: Implications for HAM/TSP DiseaseDear Editor , Human T lymphotropic virus type 1 (HTLV-1) is the aetiological agent of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), a neurological disease characterised...