Fecal Transplant Safety Is Goal of Stool BankJohnson, Carolyn Y
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difficile infection (rCDI) is an urgent public health threat, for which the last resort and lifesaving treatment is a fecal microbiota transplant (FMT). However, the exact mechanisms that mediate a successful FMT are not we... Arthur S. McMillan,Guozhi Zhang,Michael K. Dougherty,... - 《...
The researchers used a fecal microbiota preparation (FMP) consisting of stool from two different healthy donors that had been screened and purified. This two-donor preparation was used in order to maximize the diversity of bacteria in the transplant. They then used a colonoscopy to transplant the ...
A fecal microbial transplant—giving a recipient fecal matter from a donor to change the recipient's gut microbial community in the colon—has been a successful last resort therapy for people with recurrent Clostridium difficile infection after multiple
Antibiotic (Abx) treatment and fecal transplants Commensal bacteria are required for normal development, especially of the immune and nervous systems; we used a model of Abx-induced dysbiosis according to a previously published protocol [28]. The Abx compounds were applied via the drinking water fo...
Although coronary artery and aortic valve surgery studies present opposing results, the impact of these procedures on subsequent heart transplants has not been investigated scientifically.Our department's patient records indicate 235 HTx procedures were carried out on patients between 2010 and February ...
Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients. Science 371, 595–602 (2021). CAS PubMed PubMed Central Google Scholar Baruch, E. N. et al. Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients. Science 371, 602–...
Early germline genetic testing during patient evaluation facilitates the strategic planning of allogeneic stem cell transplantation, optimizing donor selection and post-transplant preventive measures. For a thorough understanding of testing data, health care providers should pay attention to how molecular ...
Patients with advanced tumor staging and positive lymph node status in post-transplant de novo upper tract urothelial carcinoma experienced a lower rate of cancer-specific survival, thus underscoring the critical role of early diagnosis. Aristolochic acid was associated with a pattern of tumors ...