Summary Factor V Leiden is the most common inherited trait in Caucasians that predisposes individuals to venous thrombosis. However, it is almost absent amongst the Basque people that live in the south western part of Europe. To explain this finding, we speculate upon the putative contribution of...
- 《Blood》 被引量: 85发表: 2001年 The association of factor V Leiden with myocardial infarction is replicated in 1880 patients with premature disease See also Tosetto A. Thrombophilic mutations and cardiovascular disease: the case is still open. This issue, pp 2113–5.Summary. Aims: Gain-...
5. Risk factors for clinical manifestation in carriers of Factor V Leiden and prothrombin gene mutations. [D] . De Sancho, Maria. 2009 机译:因子V Leiden和凝血酶原基因突变携带者临床表现的危险因素。 6. Factors Influencing Healthcare Experience of Patients with Self-Declared Diabetes: A Cross...
The factor V Leiden mutation increases the risk of venous thrombosis in patients with inflammatory bowel disease Thromboembolic disease is a significant cause of morbidity and mortality in patients with inflammatory bowel disease (IBD). The aim of this study was to de... HA Liebman,N Kashani,D...
FR Rosendaal - 《Blood》 被引量: 899发表: 1997年 Association between factor V Leiden mutation and coronary artery disease in the northeast region of Turkey Factor V Leiden (FVL) has recently been described as a genetic factor with a propensity towards ; however, it is thought to have a dou...
Prevalence of factor V Leiden and the G20210A prothrombin-gene mutation in inflammatory bowel disease A hypercoagulable state has been hypothesized as a contributing factor in the pathogenesis of inflammatory bowel disease (IBD); moreover, such patients hav... A, Papa,VD Stefano,A, Gasbarrini...
Introduction: Thrombophilia is a hemostatic disorder that defined as a tendency to thrombosis. It can be hereditary and acquired. Hereditary thrombophilia is responsible for approximately 40% of all thrombotic events. Case Report: Factor v Leiden mutation is the most common hereditary disorder in patie...
Pua et al. recently analyzed the impact of DM on myocardial fibrosis in asymptomatic individuals with HTN, and found that diabetics had lower strain and higher replacement fibrosis, as well as upregulation of GDF-15 (growth differentiation factor 15), which was independently associated with ...
E Attvall,A Frigyesi,B Sternby 摘要: Background and aims Resistance to activated protein C (APCR) caused by the Leiden mutation to factor V is the most common cause of inherited thrombosis. Patients with inflammatory bowel disease (IBD) are considered to have an increased risk of ...
Cerebral small vessel disease is characterised by decreased cerebral blood flow and blood–brain barrier impairments which play a key role in the development of white matter lesions. We hypothesised that cerebral hypoperfusion causes local hypoxia, affec