The IC50 values that were observed suggest that some of these OH-PCBs have inhibitory effects at concentrations near the concentration of endogenous hormone required for half-maximal velocity of sulfation and, thus, might alter intracellular steroid hormone signaling. We isolated cytosolic fractions from...
Our objective was to determine whether estradiol (E2) plays a role in the regulation of macrophage-nerve cross talk in endometriosis by exploring both the expression of ERs in human tissue samples and the impact of E2 on nerves and macrophages using in vitro and in vivo models. Materials and...
These enzymes induce the conversion of testosterone to estradiol to initiate ovary differentiation or dihydrotestosterone to initiate testes differentiation, respectively. Genes that code for the production of aromatase or 5-reductase are turned on or off depending on temperature. Yolk steroid hormones, ...
microorganisms, and (V) the inhibitory effect of SSRIs in the estradiol-serotonin-prolactin axis. These features are important in the overproduction of reactive oxygen species, responsible for different harmful activities such as higher cell membrane permeability and porosity, hyperstimulation of transcript...
LH and FSH in turn regulate sex hormone production (i.e., estradiol in females and testosterone in males) and the maturation of the gametes. In rodents, pheromones are known to modulate GnRH neuronal activity in a sex-dependent manner11,12. Exposure to female pheromones activates GnRH neurons...
(CYP11B2), an aldosterone synthase12. Aldosterone, a steroid hormone secreted by adrenal cortex, is the principle mineralocorticoid controlling sodium and potassium balance12. Aldosterone can bind to the mineralocorticoid receptor (MR) and induce several target genes13,14. MR has an equal affinity ...
This research delved into miR-140-3p's role in modulating chicken gastric cancer cell proliferation and steroid hormone synthesis. Dramatic increases in GC proliferation, the prevention of apoptosis, boosted progesterone synthesis, and an enhancement of gene expression for steroid hormone production were...
Lp(a) lipoprotein (a) Plasma sex hormone-binding globulin (SHBG)1 binds testosterone and estradiol with high affinity and selectivity, and regulates the access of these sex steroids to their target tissues (1). Hepatocytes are the primary site of plasma SHBG biosynthesis, and changes in the bl...
17-尾-Estradiol (E2) is a steroid hormone involved in numerous brain functions. E2 regulates synaptic plasticity in part by enhancing NMDA receptor functio... S Zadran,Q Qin,X Bi,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 159发表: ...
Google Share on Facebook T-E (redirected fromtestosterone and estradiol) AcronymDefinition T-Etestosterone and estradiol Copyright 1988-2018AcronymFinder.com, All rights reserved. Suggest new definition Want to thank TFD for its existence?Tell a friend about us, add a link to this page, or visi...