Aminoglycosides and fluoroquinolones induce membrane damage and cytoplasmic condensation in E. coli To probe how aminoglycoside, fluoroquinolone, and β-lactam antibiotics kill metabolically active bacterial cells, we treated log-phase E. coli with the aminoglycoside kanamycin, the fluoroquinolone ciprofloxaci...
Global regulators are responsible for the up and down regulation of genes across a heterogenous array of functional groups, and they are an integral facet of the hierarchical structure of the TRN in E. coli3. The altered activity of these TFs in the treated population suggests that the cells ...
coliβ-glucuronidase alters the mixture’s bioactivities. PHY906 treated with β-glucuronidase was found to exhibit stronger Wnt3a potentiation activity and anti-TNFα activity but weaker anti-iNOS activity in vitro[33]. Thus, using antibiotics to deplete intestine bacteria, which have high β-...
To eliminate the possibility that the high level of AMP gene expression was due to the presence of an ongoing infection, and not the nub1 mutation, we treated flies with a potent cocktail of antibiotics prior to the analysis. Antibiotic-treated and untreated flies promoted similar levels of ...
Escherichia coli is the commonest organism responsible for urinary tract infection and diarrhoea specially in developing countries like India. Probiot..Jagriti SharmaD. S. ChauhanAnkur Goyal
Caution is also advised in prescribing antibiotics in patients with grossly bloody diarrhea. This is because one of the common causes of grossly bloody diarrhea is Enterohemorrhagic E-coli (AKA E-coli 0157-H7). Various studies (including one published in the New England Journal of Medicine in ...
Escherichia coli from Nigeria exhibit a high prevalence of antibiotic resistance where reliance on antibiotics in poultry production is a potential contrib... Escherichia coli from Nigeria exhibit a high prevalence of antibiotic resistance where reliance on antibiotics in poultry production is a potential...
Expression vectors with inserts corresponding to ADI WT or ADI C400A were used for the transformation of chemically competent E. coli BL21-CodonPlus (DE3)-RIL (Agilent, cat. no. 230,245). Transformants were then grown overnight at 37 °C in standard Luria-Broth (LB) medium with 50 µ...
Human triosephosphate isomerase (HsTIM) is a central glycolytic enzyme and is overexpressed in cancer cells with accelerated glycolysis. Triple-negative breast cancer is highly dependent on glycolysis and is typically treated with a combination of surger
This exposure is disproportionate to the burden of disease, as only 0.5 to 2% of neonates treated with antibiotics have a culture-proven bacterial infection11. During the last decades, the impact of misuse and overuse of antibiotic therapy on growing antimicrobial resistance (AMR) has been ...