Role of mitochondria in apoptosis induced by the 2‐5A system and mechanisms involved The 2-5A system (2-5OAS/RNaseL) is composed of the 2',5'oligoadenylate synthetase 1 (2-5OAS1) and 2-5A-dependent RNase (RNaseL), enzymes that play a key ro... E Domingo-Gil,M Esteban - 《Apopt...
The DNA present in the mitochondria of the cell is termed mitochondrial DNA. It is inherited from the mother to the child. In humans, there are approximately 16,000 base pairs of mitochondrial DNA. Similarly, plastids have their own DNA, and they play an essential role in photosynthesis. ...
Publication » Mitochondriai DNA (mtDNA) is unmethylated in both somatic and germinal cells of rats.doi:10.1016/0093-691X(92)90255-PA.A. AlcivarM.P. DooleyN.B. HechtM.H. PinedaTheriogenologyAlcivar AA, Dooley MP, Hecht NH, Pineda MH. 1992. Mitochondrial DNA (mtDNA) is unmethylated in...
Mitochondria contain their own genome, known as mitochondrial DNA (mtDNA), which is circular, intron-free, double-stranded, haploid, and approximately 16.6 kb8. The mitochondrial DNA copy number (mtDNA-CN) refers to the number of mtDNA copies per cell and it can be conveniently determined from...
Alternatively, it is possible that this enzyme plays an additional, as yet undefined, role in the cell, thereby mandating its continued production. 展开 关键词: Humans Mitochondria Hela Cells Tumor Cells, Cultured Transcription Factors DNA Primers DNA, Mitochondrial Xenopus Proteins DNA Polymerase III...
The mutation rate of mitochondrial DNA is usually very high, and with enough sequence length the error in reconstructing the true species' genealogy should be small (even if the definition of 'enough sequence length' can be problematic; Ballard and Whitlock, 2004). If the time scale for ...
aNearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitohondrial DNA or mtDNA). 几乎每个细胞在人的身体有同样脱氧核糖...
AURKA is predominantly famous as an essential mitotic kinase. Recent findings have also established its critical role in a plethora of other biological processes including ciliogenesis, mitochondrial dynamics, neuronal outgrowth, DNA replication and cell
Carnitine palmitoyltransferase-1 (CPT1) is an enzyme located on the outer mitochondrial membrane that transports long-chain fatty acids into mitochondria for β-oxidation, thus controlling the rate of mitochondrial fatty acid oxidation (FAO). We recently described knockout mouse model with skeletal...
Resistance artery vasodilation in response to hypoxia is essential for matching tissue oxygen and demand. In hypoxia, erythrocytic hemoglobin tetramers produce nitric oxide through nitrite reduction. We hypothesized that the alpha subunit of hemoglobin e