Dimethyl sulfoxide (DMSO) is widely used as a vehicle solvent in ecotoxicity bioassays.Despite its frequent use, it could be toxic for organisms at some concentrations. Hence, this study aims to investigate the effects of DMSO on the model organisms: microalgae Raphidocelis subcapitata, micro...
Sodium sulfide at room temperature pure product is colorless or slightly purple prism crystal, industrial products because of impurities often pink, brown red, earth yellow block, itself is a certain odor, its solubility can be dissolved in cold water, very easy to dissolve in hot water, slightl...
(Azwanida, 2015) using solvents such as water, ethanol, methanol, chloroform, dimethyl-sulfoxideetc.However, these techniques are demanding regarding the extraction process duration, organic solvent consumption, and lack of extraction automation. The potential and powerful alternative to conventional ...
Dysregulation of gut microbial bilirubin reduction affects serum bilirubin levels, which can have substantial health implications. In moderate concentrations, bilirubin serves as an important antioxidant with potential health benefits6,7. However, elevated serum bilirubin concentrations can become toxic, leadin...
For the MG132 assay, HEK293T were treated with 5 μM of MG132 (Sigma) or DMSO (dimethyl sulfoxide) as a control. NSC34 cells were treated with 10 µM of MG132 for 24 h. Seahorse assay The seahorse assay was performed to measure the OCR (oxygen consumption rate) in ATG5 ...
This insufficient clearance and/or degradation by cells creates sizable intracellular accumulations of the aggregation-prone Aβ1–42 isoform, which further promotes cell-to-cell transfer; thus, oAβ1–42 is a potentially toxic isoform. Furthermore, cell-to-cell transfer is shown to be an early...
Finally, SN38-SS-CST NPs demonstrated potent antitumor efficacy on both cell studies and in vivo studies without additional toxic effects. Overall, SN38-SS-CST NPs overcame the dilemma of commercial Campto and highlighted the translational prospective. 4. MATERIALS AND METHODS 4.1 Materials SN38, 3...
In plants, vesicle trafficking is involved in the transport of toxic substances to resist pests and pathogens66,67. Here, we found that the insect hijacked the plant vesicle trafficking system to distribute their own effectors. This supports the idea that both insects and microbial pathogens use ...
CdCl2 (ultrapure water–dissolved) and JQ1 (dimethyl sulfoxide-dissolved) were separately stored at 4 ℃ and − 20 ℃, and diluted into working solutions before use. The experimental design was as follows: (1) Cells were treated with 0, 2.5, 5, 10 μM Cd for 12 h, or 5 μM Cd ...
DMSO dimethyl sulfoxide Keywords Adult hemoglobin Fetal hemoglobin Supercoiled plasmid DNA DNA cleavage Cysteine Protein radicals 1. Introduction Hemoglobin (Hb) is a tetrameric protein, composed of two alpha (141 residues) and two beta (146 residues) chains, forming an α2β2 heterotetramer of 64...