Diastolic dysfunction (DD) is the hallmark of HFpEF but it is unclear why some patients do not develop symptoms and remain in preclinical DD (PDD) stage with the same degree of DD as patients with HFpEF. We assumed that patients with HFpEF might have more deteriorated global myocardial work ...
A simultaneous LV pressure is necessary to measure the mean LV diastolic pressure and LV end-diastolic pressure (LVEDP) to determine whether LV diastolic dysfunction is present. The absence of a gradient between the PAWP and the mean LV diastolic pressure will rule out hemodynamically significant pu...
Sildenafil enhances systolic adaptation, but does not prevent diastolic dysfunction, in the pressure-loaded right ventricle. Eur. J. Heart Fail. 14, 1067–1074 (2012). CAS PubMed Google Scholar Cannon, M. V. et al. The liver X receptor agonist AZ876 protects against pathological cardiac ...
echocardiographic frames show end-diastolic and end-systolic apical 4-chamber views with apical aneurysmatic evolution and severely reduced ejection fraction, transmitral pulsed wave Doppler, and annular TDI displaying grade III diastolic dysfunction and transtricuspid continuous wave Doppler demonstrating seve...
Type 2 diabetes (T2D) is associated with coronary microvascular dysfunction, which is thought to contribute to compromised diastolic function, ultimately culminating in heart failure with preserved ejection fraction (HFpEF). The molecular mechanisms remain incompletely understood, and no early diagnostics ar...
Three consecutive measurements were taken, and the average of systolic blood pressure (SBP) and diastolic blood pressure (DBP) was recorded as the measurement result. Since 2014, blood pressure has been measured by a HEM-8102A electronic sphygmomanometer manufactured by Omron (Dalian, China) Co.,...
WC ≥ 90 cm in men or WC ≥ 85 cm in women. Blood pressure was measured by a mercury sphygmomanometer in a sitting position. Three consecutive measurements were taken, and the average of systolic blood pressure (SBP) and diastolic blood pressure (DBP) was recorded as the measuremen...
10 showed a sustained reduction in diastolic BP of ~4.5 mmHg over 10 days, with a high-nitrate Japanese traditional diet, compared to a low-nitrate control diet 10. In the same year, Vanhatalo et al. reported that the blood pressure-lowering effects of daily beetroot juice persisted over ...
M-mode LV end-systolic and end-diastolic dimensions were measured, and the percentage of LV fractional shortening was calculated as previously described (10). Studies were performed by investigators blinded to genotypes and heart conditions. Serial studies were performed on the day of and at 1 ...
HFrEF was the only group with a positive median value (11.6 cm(2)), and net hydraulic force was throughout diastole directed toward the atrium. The net hydraulic force may impede cardiac filling throughout diastole in HFpEF, worsening diastolic dysfunction. In contrast, it may work favorably ...