proteins and other structures of the cell live. Also known as the cytoplasmic matrix, it constitutes most of the intracellular fluid (ICF). Cytosol is often confused with cytoplasm, however, which is an entirely different entity within a cell. ...
(d) Immunoblots of proteins located in nucleus (PARP1), ER (Calnexin), Golgi (GM130), mitochondria (NDUFS3), and cytoplasm (PSPH and tubulin) in cytosolic and organellar fractions. Cytochrome c is used as a control for intact organelles (mitochondria). Data are shown as mean ± s.d....
O43504 LAMTOR5, HBXIP, XIP Ragulator complex protein LAMTOR5 (Hepatitis B virus X-interacting protein) (HBV X-interacting protein) (HBX-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5) 3 7832.41 417.52 LysosomeCytoplasm, cytosol Q6IAA8 LAMTOR1, C11orf59, ...
PKCα is localized in the cytoplasm of proliferating cells of intestinal crypts (C) and in mitotic cells of the basal/parabasal cell layers of the stratified squamous epithelium of the cervix (B). Postmitotic, mature cells of the intestinal villus (V) and of the suprabasal layers of the ...
Importins capture cargoes in the cytoplasm, release them upon encountering RanGTP inside nuclei, before returning to the cytoplasm for GTP-hydrolysis and another round of transport. Importin-7 (Imp7) is a member of the importin-β superfamily of NTRs that can act autonomously or in association ...
Despite possessing their own genome, the vast majority of proteins in chloroplasts are nuclear-encoded, synthesized as precursor proteins in the cytoplasm and transported to the chloroplast. For example, in Arabidopsis, approximately 2100–3600 proteins are synthesized in the cytosol and imported into ...
At sites where γ-cleavage occurs, cleavage will release the APP C-terminal and its paGFP tag into the cytoplasm, decreasing the fluorescent signal over time. Figure 1 Overview of constructs. For these experiments, APP constructs were generated including the full length APP 751 fused to paGFP ...
As shown in Figure 2B, except for the three newly found members, all these proteins form puncta in the cytoplasm and co-localize to autophagosomal marker p62 [36]. In contrast, none of the new isoforms could be localized to autophagosomes but only ubiquitously disperses in the cytosol, even...
Using immunohistochemistry, we unexpectedly found that, in normal human tissues, HDAC8 is exclusively expressed by cells showing smooth muscle differentiation, including visceral and vascular smooth muscle cells, myoepithelial cells, and myofibroblasts, and is mainly detected in their cytosol. These ...
Previous reports have shown that ASD subjects have impairment in the translocation of Nrf2 from the cytoplasm to the nucleus, thus leading to diminished antioxidant response [26,40,62]. This was confirmed by using the Nrf2 activator sulforaphane, which achieved upregulation of Nrf2-mediated proteins...