P093 DNA Methylation in CTC and ctDNA is A Promising Marker for Early Detection of Lung Cancer Metastasisdoi:10.1016/j.jtho.2018.10.106X. QiuQ. ZhouJournal of Thoracic Oncology
Among liquid biopsy samples, blood contains considerable genetic and proteomic information related to tumors, such as circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA). A CTC is a cancer cell that has detached from a solid tumor lesion and entered the peripheral blood circulation ...
Blood contains two types of cancer-derived materials that are susceptible to detailed molecular analysis: intact circulating tumor cells (CTCs) and cell-free circulating tumor DNA (cfDNA; also referred to as circulating tumor DNA, or ctDNA). As tumors increase in volume, the capacity of phagocyte...
The main components released by primary or metastatic tumors in a LB are circulating tumor cells (CTC), cfDNA, ctDNA, microRNA (miRNA), tumor-educated platelets (TEP), and exosomes, among others; the first three components are the most studied [19]. Exosomes are small membrane vesicles ...