FRUSEMIDE IS ELIMINATED SLOWLY IN NEONATESdoi:10.1007/BF03297896Inpharma Weekly -Springer International PublishingInPharma
We then analyzed the requirement of GSDMD in inflammasome-mediated IL-1β production. The cells were primed with LPS and then treated with nigericin. IL-1β in the culture medium was almost completely eliminated inGsdmd−/−RAW-asc cells and its production was restored when GSDMD-Flag but ...
we have found that CtIP, a core DNA end resection factor that is also required for ATR activation, plays additional roles in DNA damage-induced RNA splicing28. Interestingly, we could see that CtIP downregulation specifically eliminated the DNA damage...
While the majority of studies so far indicate that delivery mode is the strongest factor determining early neonatal gut microbiome colonization3,7,8,9,10,18, these effects are either extenuated or largely absent in other studies11,19. In this context, it is important to consider that CSD may...