Its activity does coincide with changes in the inner membrane permeability and activity by other SCLEs (CwlJ1 and 2), so it is possible that those two events play a role in activating SleB [153,250]. However, a co-expressed peptide (YpeB) is essential to properly localize SleB and ma...
Molecular dynamics simulations of these two cations paired with hexafluorophosphate in the pure state and mixed with CO_2 are also described. Both the experimental and the simulation results indicate that the anion has the greatest impact on the solubility of CO_2. Experimentally, it is found ...
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Apoptosis caused by loss of Par3 is cell autonomous We next asked if apoptosis triggered by depletion of Par3 is cell autonomous. NMuMG cells were transduced separately with lentivirus to express shLuc plus YFP, or shPar3 plus RFP, then mixed at a 1:1 ratio and co-cultured. Three days ...
Most of the ongoing projects aimed at the development of specific therapies and vaccines against COVID-19 use the SARS-CoV-2 spike (S) protein as the main target. The binding of the spike protein with the ACE2 receptor (ACE2) of the host cell constitutes the first and key step for vir...
Huawei Investment & Holding Co., Ltd. 2016 Annual Report Who is Huawei? Huawei is a leading global information and communications technology (ICT) solutions provider. Driven by a commitment to sound operations, ongoing innovation, and open collaboration, we have established a competitive ICT ...
In the present study, we further show that coexpression of GDE3 with GPR55 abrogates interaction of LPI with GPR55, whereas at the vicinity of CB2, GDE3 allows LPI to evoke signaling events identical to those induced by 2-AG. Finally, invalidation of mouse GDE3 gene (Gdpd2) resulted ...
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