Psychostimulants such as amphetamine or NMDA receptor antagonists such as MK-801 induce psychotic symptoms in normal humans and exacerbate such symp- toms in schizophrenic patients. As such, the ability of antipsychotic drugs to antagonize locomotor responses to such challenges is taken as a measure...
These includestimulant medicationsto treat ADHD (attention deficit hyperactivity disorder), such as methylphenidate, dexamfetamine and lisdexamfetamine. Antipsychotic medications(such as clozapine, olanzapine and quetiapine) used to treatmental health conditions, such as schizophrenia andbipolar disorder, are ...
Tofranil is a mood-elevating drug that would be classified as a(n) a. minor tranquilizer. b. major tranquilizer. c. antidepressant. d. anxiolytic Mood: Mood-elevating drugs work to target neurotransmitters in the brain that ...
Clozapine and the novel putative, antipsychotic S 16924 ((1-(benzodioxane-5-yl)-3-[3-(4-fluorophenacyl)pyrrolidine]-1-o xapropane HCl) share significant af... H Jörgen Bengtsson,A Kullberg,MJ Millan,... - 《Neuropharmacology》 被引量: 225发表: 1998年 Modulation of human cardiac functi...
Which of the following is not an effect of the drug (Clozapine)? (a) Agranulocytosis (b) Antipsychotic (c) Used for Schizophrenia (d) Increased appetite. What is the effect of the contraindication of antihistamines with patients taking MAOIs? a. ...
This can lead to increased serotonin levels which could cause a serotonin syndrome. People taking SSRIs should also avoid taking pimozide (an antipsychotic diphenylbutylpiperidine derivative). The atypical opioid analgesic tramadol hydrochloride (or Ultram, Ultracet) can, in rare cases, produce seizures...
Human 5C-CPT task The participants were given a brief introduction to the task. The subjects were forewarned that they would see 5 white lines (3 cm) in an arc on a black background and if a white circle (B2 cm diameter) appeared behind a line then they should move the joystick in ...
The prefrontal cortex (PFC) is believed to play an important role in the cognitive impairments observed in schizophrenia and has also been shown to be involved in the modulation of prepulse inhibition (PPI), a measure of preattentive information processi
Systemically administered PCP increases the firing rate of dopaminergic neurons (Freeman and Bunney, 1984; French et al, 1993), and dopamine receptor antagonists, including antipsychotic drugs such as haloperidol and clozapine, attenuate PCP-induced stereotypies and locomotion (Sturgeon et al, 1981; ...
To determine whether the ability to produce locomotor stereotypy is an exclusive property of amphetamine or is a property of many amphetamine-like stimulants, several doses of methylphenidate and amfonelic acid were tested. The ability of both atypical and typical neuroleptics to block amphetamine-...