Cilostazol is an antiplatelet agent with vasodilating properties that has been used in the treatment of patients with peripheral ischaemia such as intermittent claudication. The drug inhibits platelet aggregation induced by ADP, collagen and arachidonic acid. Unlike aspirin (acetylsalicylic acid), ...
摘要: Whether antiplatelet agents have a preventive effect on cognitive function remains unknown. We examined the potential association between the use of cilostazol, an antiplatelet agent and cyclic adenos关键词:Dementia cilostazol cohort studies ...
More research is needed in this area to better adjudicate the role of cilostazol in addition to aspirin and clopidogrel. Thus clopidogrel is used as an effective antiplatelet agent in a variety of situations, including ACS, stable CAD, PAD, stroke, after TAVR, and as double therapy for atrial...
Antiplatelet therapy (presence/absence) 0.62 (0.33-1.22) .16 Aspirin (presence/absence) 1.03 (0.57-1.88) .93 Ticlopidine/clopidogrel (presence/absence) 1.24 (0.60-2.37) .54 Cilostazol (presence/absence) 0.82 (0.40-1.54) .54 SAPT (presence/absence) 0.50 (0.27-0.89) .02 0.46 (0.24-0....
In fact, PDE inhibitors (cilostazol, dipyridamole) have been used as antiplatelet materials to increase cyclic nucleotides production [28]. Therefore, it is thought that CXB could be developed as an antiplatelet agent through increasing cyclic nucleotides....
RACTS: A Prospective Randomized Antiplatelet Trial of Cilostazol Versus Ticlopidine in Patients Undergoing Coronary Stenting We compared the efficacy of cilostazol for the prevention of late restenosis and acute or subacute stent thrombosis with that of ticlopidine. Cilostazol ha... J Ge,Y Han,H Jian...
• However, TAT with cilostazol remains an attractive choice to optimize therapy in high-risk patients (e.g., STEMI) and those with high residual reactivity on clopidogrel, in particular: – CYP2C19 poor metabolizers – Patients at high bleeding risk – Patients with high risk of restenosis ...
Medications were grouped into (i) antiplatelet aggregating agents (Ecospirin, Clopidogrel, Cilostazol), (ii) Antihypertensive agents (Calcium channel blockers, ACE inhibitors, vasodilators), (iii) Statins (atorvastatin, Lovastatin) and (iv) Metformin derivatives (glucophage, glycimet). Statistical ...
Adjunctive Cilostazol Versus Double-Dose Clopidogrel After Drug-Eluting Stent Implantation: The HOST-ASSURE Randomized Trial (Harmonizing Optimal Strategy ... Objectives This study sought to test the noninferiority of triple antiplatelet therapy (TAT) versus double-dose clopidogrel dual antiplatelet therapy...
Meta-analysis of results from eight randomized, placebo-controlled trials on the effect of cilostazol on patients with intermittent claudication. We examined the effect of cilostazol, a type III phosphodiesterase inhibitor, on pain-free and maximal walking distance and quality of life measures. The p...