Benzamidines are generally associated with poor oral bioavailability, which is explained by the strong basic character of the amidine group and the formation of a stable cation23,24. To improve oral bioavailability several strategies have been employed, including mimetic replacement of the amidine group...
Fisher Scientific: isopropanol, dimethylacetamide, dichloromethane, dimethylformamide, diisopropylethylamine, 3-nitrobenzamidine, 3-aminobenzamidine; tin(II) dichloride dihydrate, formic acid, acetonitrile, 4-trifluoromethylaniline, 3-chloroaniline, 2-bromoaniline, 2-aminobenzonitrile, 10 NATURE COMMUNICATIONS | ...