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Overall survival is the “gold standard” endpoint in cancer clinical trials. It plays a key role in determining the clinical- and cost-effectiveness of a new intervention and whether it is recommended for use in standard of care. The assessment of overa
'Slightly overweight' Brits TWICE as likely to face diabetes hell; Average adult in risky weight range; Fears for the 18.5m with a few lbs to lose In 1993, when the survey began, just 1% of women were classed as morbidly obese, according the data from NHS Digital. Fifth of women morbid...
For those who have had scabies before, symptoms can occur in as little as 24 hours. It is important to know that even when symptoms are not present, scabies can still spread. Is scabies a sexually transmitted infection? Scabies can be classed as a sexually transmitted infection (STI), ...
Only last week one medical journal revealed how obesity was fuelling a rise in cancer cases. Obesity also increases the risk factor for strokes and heart disease. An averagely obese person"s lifespan is shortened by around nine years while a severely obese person by many more. Prof Prentice ...
Integrative multi-omics analyses identify c-Jun as the core signaling node in ZBTB7B-deficient liver cancer initiation. c-Jun is a direct target of ZBTB7B essential to accelerated liver cancer initiation in ZBTB7B-deficient livers. Knockdown of c-Jun expression or dominant negative c-Jun ...
Knowing your body fat percentage can be a good measure of fitness and functionality, says Dr Steven Heymsfield, professor at Pennington Biomedical Research Centre. For men aged 20-39, a score of above 25 per cent is classed as obese, for gents aged 40-59, this cut off point is raised ...
Acute lymphoblastic leukemia (ALL) is the most common malignancy and cancer-related cause of death at pediatric age [1, 2]. Despite a considerable success rate of standard chemotherapy treatments, as many as 10–15% of children with ALL have recurrent disease (relapses) [3, 4]. Patients wi...
classed as those that moved at a velocity less than that of an erythrocyte down a 100 μm segment of vessel. Adherent cells were classed as those that were stationary for 30 s or longer within the 100-μm segment of vessel [17]. Data are shown as mean ± SEM. For comparisons ...
What other disease states may be amenable to microbiome-based interventions? There are diseases that are caused by known genetic mutations. Yet, for nearly all of them, there is great variation in clinical outcomes, which might be classed as genes multiplied by environment interactions. ...