This case drew national attention in 2018. About 100 people died and more than 300 hospitalized in a span of few years in a village of 1200 people in a tribal stretch in central India. Medical teams visiting the area reported severe renal failure and bla
We propose a strategy to alleviate doxorubicin induced cardiomyopathy by blocking Abl1 activity. Additionally, we gained deep insight into the genomic responses of cardiomyocytes as they relate to mitochondrial toxicity, programmed cell death, inflammation and toxic cardiomyopathy that is orchestrated, at ...
Which vitamin if taken in excess can be toxic to the body? Q. Necrosis in crops is due to the deficiency of w 1 answer below Q. Necrosis in crops is due to the deficiency of which ions/elements? Calcium, phosphorous, potassium, zinc Sulphur...
The most frequent toxic reaction was reversible bone marrow suppression, which was reversed by reducing the dosage. The major drawbacks of DFMO are its cost and the duration of treatment and availability. DFMO is not trypanocidal and depends on a functional immune system to rid the host of non...
Ammonium (NH4+), a breakdown product of amino acids that can be toxic at high levels, is detected by taste systems of organisms ranging from C. elegans to humans and has been used for decades in vertebrate taste research. Here we report that OTOP1, a pro
fatal — it was used as a chemical weapon during World War I — but is unlikely in everyday situations. Household bleach can, however, be dangerous if mishandled. It can release large amounts of the gas on contact with acids, and combines with products containingammoniato form toxic ...
These ions have little or no short-term effects, but toxic ions (lead arsenic, cadmium, nitrate, and others) may also be dissolved in the water. Even the best water purification systems on the market require monitoring for TDS to ensure the filters and membranes are effectively r...
Metabolism of haem by-products such as bilirubin by humans and their gut microbiota is essential to human health, as excess serum bilirubin can cause jaundice and even neurological damage. The bacterial enzymes that reduce bilirubin to urobilinogen, a ke
4. As salmon lice display sexually dimorphic patterns of mobility (i.e. mate location [32] and fre- quency of host switching [31]) and responses to neuro- toxic drugs [37, 44], these transcripts will serve as important markers to better understand sex-related dif- ferences in the L. ...
2P). According to the literature, the toxic oligomers of Aβ42 (oAβ42) can lead to synaptic loss [16], which may be one of the key reasons for the synaptic loss caused by GNG5 overexpression. In this part, we found GNG5-induced synaptic loss in wild-type primary neurons, which ...