Sometimes, an acquired condition, such as AIDS, can be associated with cerebral atrophy and degenerative dementia.Wernicke-Korsakoff syndromecan cause progressive brain atrophy and behavioral changes in association with alcohol abuse. Some experts suggest that aging is associated with slowly progressive atr...
In a longitudinal population-based study, we investigated the association of brain atrophy with decline in activities of daily living (ADL) during a 6-year follow-up period. Methods At baseline (2002-2008), 2991 (mean age 60 years, 54% female) non-demented participants from the population-...
Aim: Falls are common in patients with cognitive disorder. The purpose of this study was to determine whether global brain atrophy is associated with cognitive function, physical performance and fall incidents in older adults with mild cognitive disorder.Methods: A total of 31 older adults with mil...
I have brain atrophy. I did have it when I was born. I feel OK anyway about my living with it. I am so used to having it. I am 48 years old now. One big problem though, is that people think automatically that someone like me is stupid, which I am not. My problems are that ...
We found that GlycA was elevated in AD patients compared to cognitively normal participants. GlycA correlated negatively with multiple concurrent regional brain volumes in females diagnosed with late mild cognitive impairment (LMCI) or AD. Baseline GlycA level was associated with executive function ...
Data distribution was assumed to be normal but this was not formally tested. The correlations between two data in the same genotype group were analyzed using simple linear regression. The analyses were performed and plots were created with GraphPad Prism v.9.2.0. For immunohistochemical, ...
Wen WSachdev PS The topography of white matter hyperintensities on brain MRI in middle-aged individuals. Neuroimage 2004;22141- 154Google ScholarCrossref 28. Fazekas FChawluk JBAlavi AHurtig HIZimmerman RA MR signal abnormalities at 1.5 T in Alzheimer’s dementia and normal aging. AJR Am J...
With respect toAPOEgenotype effects on AD pathology, the most compelling results published to date describe the differing regional patterns of brain atrophy observed inAPOE4+ vs.APOE4−AD patients. While a couple of studies have not observed any differences in brain volume or cortical thickness ...
Pattern 1: IdC integrity is associated with whole-brain covariance of neurite density and orientation dispersion The first significant LV explained 26.9% of total crossblock covariance (p < 0.0001) (Fig. 3). R1, MTsat and R2* across multiple IdC nuclei were positively associated with NDI ...
Normal donkey serum in the absence of primary antibodies was used as a negative control. After a PBS wash, the sections were incubated with secondary antibodies for one h at RT. After three washes in PBST, the sections were mounted with an anti-fading mounting medium (ProLong™ Glass Anti...