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USA; 6Department of Neurology, Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA Bipolar disorder (BP) is a debilitating psychiatric disorder, affecting B2% of the worldwide population, for which the etiological basis, pathogenesis, and neurocircuitry remain poorly understood....
409 base pairs (bp) (accession number KY964413), with a 230 bp 5′ untranslated region (UTR), a 1072 bp 3′ UTR, and an open reading frame (ORF) of 1,107 bp, which encodes a protein of 368 amino acid (aa
Insets in A and B represent lower power views to emphasize the lack of Aβ42 immunoreactivity in several neurons of APP knockout mouse brain; Aβ42 gold particles within several neuronal perikarya from wild-type mouse are evident (inset in A) compared with lack of gold particles in several...
In placental samples from diet-controlled GDM (d-GDM) pregnancies we found a lower percentage of conduit vessels showing occludin immunoreactivity (12%, p < 0.01), decreased levels of the fully functional occludin isoform-A protein (29%), and differential gene expression of OCLN variant 2 ...
These studies also indicate that Ism1-AAV8 mice have improved glucose tolerance (Figure 5D) and dramatically increased insulin sensitivity at 10 weeks (Figure 5E). While non-fasting glucose levels are not changed (Figure S5I), plasma levels of insulin are lower in the Ism1-AAV8 mice, ...
per CME probabilities, markets are only pricing-in two 25bp rate cuts by the Fed this year, the first in September and another in December. Also, the US 10Y Treasury's auction saw weak demand with a bid-to-cover of only 2.34x vs. 2.51x previously and a lower indirect bidder take-up...
we collected ten different kinds of tumour tissues and normal tissues adjacent to tumours and used immunohistochemical staining to determine the levels of isonicotinylation in these tissues. Results showed that the total Kiniclevel was lower in gastric carcinoma tissues than in normal tissues, while...
with or without continuous supplementation of vitamin B12as indicated. The lower and upper hinges correspond to the first and third quartiles (the 25th and 75th percentiles). The upper and lower whiskers extend from the hinge to the largest and smallest values, respectively, no further than 1.5...