were strongly attenuated in theOtop1−/−mouse strain, which retained sensitivity to the sweet stimulus AceK, used as a control (Fig.1a, c). A double knockout ofOtop1andSkn-1ashowed a similarly attenuated response to NH4Cl as theOtop1−/−-strain (Fig.1a, c); these mice also l...
On the other hand, it is possible that even though the brain is sending signals to produce heat, the peripheral tissue (i.e. brown adipose tissue or skeletal muscle) may not be producing heat because it does not receive the signal properly or is unable to respond to the signal. Either ...
Emuka, ATsuchiya, TTakei, NElsevier B.V.Comparative Biochemistry & Physiology Part A PhysiologySugi H, Gomi S, Toride M, Emura A, Tsuchiya T, Takei N (1985) Mechanical activity in the lantern retractor muscle of a seaurchin Anthocidaris crassispina . Comp Biochem Physiol 81 A:397–401...
For the 18S rRNA sequences, the number of nucleotide differences between 18S rRNA gene sequences are indicated in red, instead of the identity percentages. For ama-1 and rap-1a genes, percentage of identities are indicated in green and blue, respectively. Sequence identities with each rap-1a ...
based on the ischemic muscle having intact, or reduced, IL-21/IL21R signaling. In this comparison, 200 mRNAs were differentially expressed but only six microRNA (miR)/miR clusters (and among these only miR-30b) were upregulated in EC isolated from ischemic muscle. Next, myoglobin-overexpressi...
Subsequently, FRAP reagent, a combination of acetate buffer of 300 mM, pH = 3.6, 2,4,6-tripyridyl-s-triazine (TPTZ) 10 mM, and FeCl3·6 H2O 20 mM solutions in a 10:1:1 ratio, was used, and the reduction in the Fe3+–TPTZ complex to Fe2+–TPTZ (blue- colored complex) was ...