However, the function of these VDAC oligomeric structures is still not clear. We have shown that VDAC oligomerization is highly enhanced upon apoptosis, as induced by various stimuli, and is directly associated with Cyto c release (Fig. 1, Fig. 2, Fig. 3) [23], [24]. The finding that...
The main problem in assessing the impact of CMG2 in sarcoma genesis and progression lays in the still lacking data on the physiological function of this gene and the signaling pathways involved, beside the fact that CMG2 has been linked to several cellular processes. For instance, in ...