As one of the most common mental health issues, anxiety disorders are typified by overwhelming anxiety, avoidance behaviors, and impairment in social and occupational functions, often resulting in significant disability [1, 2]. However, over half of patients with anxiety disorders do not respond ...
www.nature.com/scientificreports OPEN Neuronal deletion of C aV1.2 is associated with sex‑specific behavioral phenotypes in mice Annette J. Klomp 1,2, Ashley Plumb 3, Jacqueline B. Mehr 4,5, Deniz A. Madencioglu 1,2, Hsiang Wen 1,2 & ...
Similarly, USP18 is a regulator or cell cycle, mediated by its deISGylation activity [22,29,43,44]. Also, in muscle cells, USP18 depletion leads to reduced proliferation. Yet, it was not associated with global changes in ISGylation, but instead the expression of cell cycle genes was ma...
and its close of hope in an ending supposedly occurring in contemporary times is made acceptable by the use of film techniques which signal to the watcher we are in a dream-fantasy, which includes a ghost revenant of the earlier Julien to stir the heart of now ancient Sara...
the basis of the nati the bastard smiled the battle for rome a the battle of algeri the battle of imphal the battle of orgreav the battle of the pel the battle of the som the battle of tommy g the battle of trenton the battle ofwits in the battling bishops the beans spends the the...
Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical functions in a variety of peripheral systems. Growing research has also shown that dopamine acts as an important regulator of immune function. Many immune cells express dopamine receptors and other dopamine related ...
An association between cognition and physical function has been shown to exist but the roles of muscle and brain structure in this relationship are not fully understood. A greater understanding of these relationships may lead to identification of the und
Interestingly, UBE2A (encoded at chr Xq24) is associated with neurological diseases that involve cognitive disruption, such as Alzheimer's disease (AD), Parkinson's disease (PD), mental retardation, X-linked syndrome, X-linked intellectual disability (Nascimento type), and other progressive, age-...
Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017, 390, 1211–1259. [CrossRef] 22. Eke, P.I.; Dye, B.A.; Wei...
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